磷酸变位酶1重组兔单抗
Rrmab®兔单抗
货号：bsm-60524R
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概述
产品编号
bsm-60524R
产品类型
重组兔单抗
英文名称
PGAM1 Recombinant Rabbit mAb
中文名称
磷酸变位酶1重组兔单抗
英文别名
HEL-S-35; PGAM-B; PGAMA; 2310050F24Rik; Pgam-1; Pgmut; PGAM1_HUMAN; PGAM1; BPG-dependent PGAM 1; Phosphoglycerate mutase isozyme B (PGAM-B); 5.4.2.11; 5.4.2.4; PGAM1_MOUSE; PGAM1_RAT;
抗体来源
Rabbit
免疫原
A synthesized peptide derived from human PGAMA1: 1-54/254
亚型
IgG/Kappa
性状
Liquid
纯化方法
affinity purified by Protein A
克隆类型
Recombinant
克隆号
D3C4
浓度
1mg/ml
储存液
0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
研究领域
保存条件
Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事项
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
数据库链接
背景资料
PGAM1 belongs to the phosphoglycerate mutase family, BPG-dependent PGAM subfamily. It is involved in the interconversion of 3- and 2-phosphoglycerate with 2,3-bisphosphoglycerate as the primer of the reaction.
产品应用
| 应用 | 已检合格种属 | 预测种属 | 推荐稀释比例 |
|---|---|---|---|
| WB | Human, Mouse, Rat | 1:500-2000 | |
| IHC-P | Human, Mouse, Rat | 1:50-200 | |
| IHC-F | Human, Mouse, Rat | 1:50-200 | |
| IF | Human, Mouse, Rat | 1:50-200 | |
| Flow-Cyt | Human, Mouse, Rat | 1:50-100 |
交叉反应
交叉反应: Human, Mouse, Rat
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靶标
基因名
PGAM1
蛋白名
phosphoglycerate mutase 1
亚基
Homodimer.
组织特异性
In mammalian tissues there are two types of phosphoglycerate mutase isozymes: type-M in muscles and type-B in other tissues.
翻译后修饰
Acetylated at Lys-253, Lys-253 and Lys-254 under high glucose condition. Acetylation increases catalytic activity. Under glucose restriction SIRT1 levels dramatically increase and it deacetylates the enzyme.
相似性
Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.
功能
Interconversion of 3- and 2-phosphoglycerate with 2,3-bisphosphoglycerate as the primer of the reaction. Can also catalyze the reaction of EC 5.4.2.4 (synthase) and EC 3.1.3.13 (phosphatase), but with a reduced activity.
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