Cleaves the gamma-glutamyl bond of extracellular glutathione (gamma-Glu-Cys-Gly), glutathione conjugates (such as maresin conjugate (13R)-S-glutathionyl-(14S)-hydroxy-(4Z,7Z,9E,11E,16Z,19Z)-docosahexaenoate, MCTR1) and other gamma-glutamyl compounds (such as leukotriene C4, LTC4).
产品应用
应用
已检合格种属
预测种属
推荐稀释比例
IHC-P
Human
1:100-500
IHC-F
Human
1:100-500
IF
Human
1:100-500
交叉反应
交叉反应: Human
相关产品
暂无相关产品
靶标
基因名
GGT1
蛋白名
Glutathione hydrolase 1 proenzyme
亚基
Heterodimer composed of the light and heavy chains. The active site is located in the light chain.
亚细胞定位
Membrane; Single-pass type II membrane protein.
组织特异性
Detected in fetal and adult kidney and liver, adult pancreas, stomach, intestine, placenta and lung. Isoform 3 is lung-specific. There are several other tissue-specific forms that arise from alternative promoter usage but that produce the same protein.