清道夫受体B2重组兔单抗
Rrmab®兔单抗
货号：bsm-62192R
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概述
产品编号
bsm-62192R
产品类型
重组兔单抗
英文名称
SCARB2 Recombinant Rabbit mAb
中文名称
清道夫受体B2重组兔单抗
英文别名
AMRF; CD36L2; EPM4; HLGP85; LGP85; LIMP-2; LIMPII; SR-BII; 9330185J12Rik; LIMP II; MLGP85; SCRB2_HUMAN; SCARB2; 85 kDa lysosomal membrane sialoglycoprotein (LGP85); CD36 antigen-like 2; Lysosome membrane protein II (LIMP II); Scavenger receptor class B member 2; LIMP2; SCRB2_MOUSE; SCRB2_RAT;
抗体来源
Rabbit
免疫原
A synthesized peptide derived from human SCARB2: 61-100/478
亚型
IgG
性状
Liquid
纯化方法
affinity purified by Protein A
克隆类型
Recombinant
克隆号
9F3
理论分子量
54
检测分子量
77
储存液
10mM phosphate buffered saline(pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol.
研究领域
SWISS
Gene ID
保存条件
Store at 4℃ for short term. Store at -20℃ for long term. Avoid repeated freeze/thaw cycles.
注意事项
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
数据库链接
背景资料
Acts as a lysosomal receptor for glucosylceramidase (GBA1) targeting.
产品应用
| 应用 | 已检合格种属 | 预测种属 | 推荐稀释比例 |
|---|---|---|---|
| WB | Human | Mouse, Rat | 1:500-2000 |
| IHC-P | Human, Mouse, Rat | 1:200-500 | |
| IHC-F | Human, Mouse, Rat | 1:200-500 | |
| IF | Human, Mouse, Rat | 1:200-500 | |
| Flow-Cyt | Human, Mouse, Rat | 1:50-100 | |
| IP | Human, Mouse, Rat | 1:20-50 |
交叉反应
交叉反应: Human, Mouse, Rat
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靶标
基因名
SCARB2
蛋白名
Lysosome membrane protein 2
亚基
Interacts with GBA (via the coiled-coil domain).
亚细胞定位
Lysosome membrane; Multi-pass membrane protein.
疾病
Defects in SCARB2 are the cause of progressive myoclonic epilepsy type 4 with or without renal failure (EPM4) [MIM:254900]. An autosomal recessive progressive myoclonic epilepsy associated with renal failure in some cases. Cognitive function is preserved. Myoclonus is a brief, involuntary twitching of a muscle or a group of muscles. Cognitive function is preserved.
Note=Genetic variants in SCARB2 can act as modifier of the phenotypic expression and severity of Gaucher disease.
Note=Genetic variants in SCARB2 can act as modifier of the phenotypic expression and severity of Gaucher disease.
相似性
Belongs to the CD36 family.
功能
Acts as a lysosomal receptor for glucosylceramidase (GBA) targeting.
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