硒蛋白Z重组兔单抗
Rrmab®兔单抗
货号：bsm-62166R
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概述
产品编号
bsm-62166R
产品类型
重组兔单抗
英文名称
TXNRD2/SELZ Recombinant Rabbit mAb
中文名称
硒蛋白Z重组兔单抗
英文别名
GCCD5; SELZ; TR; TR-BETA; TR3; TRXR2; TXNR2; ESTM573010; TGR; Trxrd2; TRXR2_HUMAN; TXNRD2; Selenoprotein Z (SelZ); Thioredoxin reductase TR3; 1.8.1.9; KIAA1652; TRXR2_MOUSE; TRXR2_RAT;
抗体来源
Rabbit
免疫原
A synthesized peptide derived from human TXNRD2: 50-100/524
亚型
IgG
性状
Liquid
纯化方法
affinity purified by Protein A
克隆类型
Recombinant
理论分子量
57
检测分子量
57
储存液
10mM phosphate buffered saline(pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol.
研究领域
SWISS
Gene ID
保存条件
Store at 4℃ for short term. Store at -20℃ for long term. Avoid repeated freeze/thaw cycles.
注意事项
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
数据库链接
背景资料
Involved in the control of reactive oxygen species levels and the regulation of mitochondrial redox homeostasis.Maintains thioredoxin in a reduced state. May play a role in redox-regulated cell signaling.
产品应用
| 应用 | 已检合格种属 | 预测种属 | 推荐稀释比例 |
|---|---|---|---|
| WB | Human, Mouse, Rat | 1:500-2000 | |
| IHC-P | Human | Mouse, Rat | 1:100-500 |
| IHC-F | Human | Mouse, Rat | 1:100-500 |
| IF | Human | Mouse, Rat | 1:100-500 |
交叉反应
交叉反应: Human, Mouse, Rat
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靶标
基因名
TXNRD2
蛋白名
Thioredoxin reductase 2, mitochondrial
亚基
Homodimer.
亚细胞定位
Mitochondrion.
组织特异性
Highly expressed in the prostate, ovary, liver, testis, uterus, colon and small intestine. Intermediate levels in brain, skeletal muscle, heart and spleen. Low levels in placenta, pancreas, thymus and peripheral blood leukocytes. According to PubMed:10608886, high levels in kidney, whereas according to PubMed:9923614, levels are low.
相似性
Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
功能
Maintains thioredoxin in a reduced state. Implicated in the defenses against oxidative stress. May play a role in redox-regulated cell signaling.
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