扑克蒙蛋白重组兔单抗

bsm-62165R

重组兔单抗、mIHC精品抗体

Pokemon/ZBTB7A Recombinant Rabbit mAb

扑克蒙蛋白重组兔单抗

FBI-1; FBI1; LRF; MNDLFH; TIP21; ZBTB7; ZNF857A; pokemon; 9030619K07Rik; 9130006G12Rik; ZBT7A_HUMAN; ZBTB7A; Factor binding IST protein 1 (FBI-1); Factor that binds to inducer of short transcripts protein 1; HIV-1 1st-binding protein 1; Leukemia/lymphoma-related factor; POZ and Krueppel erythroid myeloid ontogenic factor (POK erythroid myeloid ontogenic factor | Pokemon | Pokemon 1); TTF-I-interacting peptide 21 (TIP21); Zinc finger protein 857A; ZBT7A_MOUSE; POZ and Krueppel erythroid myeloid ontogenic factor (POK erythroid myeloid ontogenic factor | Pokemon);

Rabbit

A synthesized peptide derived from human ZBTB7A: 520-584

IgG

Liquid

affinity purified by Protein A

Recombinant

2B1

61

70

10mM phosphate buffered saline(pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol.

Store at 4℃ for short term. Store at -20℃ for long term. Avoid repeated freeze/thaw cycles.

This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

Pokemon(7APOK Erythroid Myeloid Ontogenic factor)能够控制将正常细胞变成癌细胞所需的途径,Pokemon蛋白是转录因子蛋白家族的一员，并且在人类癌症中发生了突变。另外Pokemon蛋白作为转录因子参与一些细胞基因转录的调节,并在细胞分化过程中发挥着关键、多效性的功能。近来发现,Poke-mon在致癌转化过程中发挥着至关重要的功能,并与肿瘤的发生密切相关。
这种蛋白很可能在实质肿瘤中处于重要地位,还有学者认为：Pokemon在一定类型的B细胞和T细胞淋巴瘤中水平非常高，并发现具有高水平Pokemon蛋白表达对肿瘤恶性程度改变更大。
主要定位于细胞核。
扑克蒙”蛋白又称“波克曼”蛋白。

Transcription factor that represses the transcription of a wide range of genes involved in cell proliferation and differentiation.