半胱氨酸蛋白酶重组兔单抗
Rrmab®兔单抗
货号：bsm-62150R
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概述
产品编号
bsm-62150R
产品类型
重组兔单抗
英文名称
Legumain Recombinant Rabbit mAb
中文名称
半胱氨酸蛋白酶重组兔单抗
英文别名
AEP; LGMN1; PRSC1; LGMN_HUMAN; LGMN; Asparaginyl endopeptidase (AEP); Protease, cysteine 1; 3.4.22.34; LGMN_MOUSE; LGMN_RAT; Asparaginyl endopeptidase;
抗体来源
Rabbit
免疫原
A synthesized peptide derived from human Legumain: 200-350
亚型
IgG
性状
Liquid
纯化方法
affinity purified by Protein A
克隆类型
Recombinant
克隆号
12C11
理论分子量
49
检测分子量
36,57
储存液
10mM phosphate buffered saline(pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol.
研究领域
Cancer > Cancer Metabolism > Metabolic signaling pathway > Hormone biosynthesis
Cell Biology > Other Antibodies > Plant related targets
Cell Biology > Proteolysis / Ubiquitin > Proteolytic enzymes > Other proteases
Immunology > Cell Type Markers > Non-CD > APC
Metabolism > Pathways and Processes > Endocrine metabolism > Hormone biosynthesis
Signal Transduction > Cytoskeleton / ECM > Extracellular Matrix > Structures > Bone
SWISS
Gene ID
保存条件
Store at 4℃ for short term. Store at -20℃ for long term. Avoid repeated freeze/thaw cycles.
注意事项
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
数据库链接
背景资料
Has a strict specificity for hydrolysis of asparaginyl bonds.Can also cleave aspartyl bonds slowly, especially under acidic conditions.Involved in the processing of proteins for MHC class II antigen presentation in the lysosomal/endosomal system.
产品应用
| 应用 | 已检合格种属 | 预测种属 | 推荐稀释比例 |
|---|---|---|---|
| WB | Human, Mouse, Rat | 1:500-2000 |
交叉反应
交叉反应: Human, Mouse, Rat
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靶标
基因名
LGMN
蛋白名
Legumain
亚细胞定位
Lysosome (By similarity).
组织特异性
Ubiquitous. Particularly abundant in kidney, heart and placenta.
翻译后修饰
Glycosylated.
相似性
Belongs to the peptidase C13 family.
功能
Has a strict specificity for hydrolysis of asparaginyl bonds. Can also cleave aspartyl bonds slowly, especially under acidic conditions. May be involved in the processing of proteins for MHC class II antigen presentation in the lysosomal/endosomal system.
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