PSMA2 | HC3/PSC3 Recombinant Rabbit mAb (一抗) - WB,IHC-P,IHC-F,IF,Flow-Cyt,ICC/IF | Bioss

bsm-62091R

重组兔单抗、mIHC精品抗体

PSMA2 | HC3/PSC3 Recombinant Rabbit mAb

蛋白酶体PSMα2重组兔单抗

HC3; MU; PMSA2; PSC2; Lmpc3; PSA2_HUMAN; PSMA2; Macropain subunit C3; Multicatalytic endopeptidase complex subunit C3; Proteasome component C3; Proteasome subunit alpha-2 (alpha-2); PSC3; PSA2_MOUSE; PSA2_RAT; proteasome 20S subunit alpha 2; proteasome (prosome, macropain) subunit, alpha type, 2; proteasome subunit alpha 2

Rabbit

A synthesized peptide derived from human PSMA2: 40-90/234

IgG

Liquid

affinity purified by Protein A

Recombinant

2H5

26 kDa

26 kDa

0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.

This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

Component of the 20S core proteasome complex involved in the proteolytic degradation of most intracellular proteins. This complex plays numerous essential roles within the cell by associating with different regulatory particles. Associated with two 19S regulatory particles, forms the 26S proteasome and thus participates in the ATP-dependent degradation of ubiquitinated proteins.

PSMA2

Proteasome subunit alpha type-2

The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits. The 20S proteasome core is composed of 28 subunits that are arranged in four stacked rings, resulting in a barrel-shaped structure. The two end rings are each formed by seven alpha subunits, and the two central rings are each formed by seven beta subunits. The catalytic chamber with the active sites is on the inside of the barrel.

Cytoplasm. Nucleus. Cytoplasm, P-body (By similarity). Note=Co-localizes with TRIM5 in the cytoplasmic bodies (By similarity).

Phosphorylated on tyrosine residues; which may be important for nuclear import (By similarity).

Belongs to the peptidase T1A family.

The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity. PSMA2 may have a potential regulatory effect on another component(s) of the proteasome complex through tyrosine phosphorylation.