PEN2 Recombinant Rabbit mAb (一抗) - WB,IHC-P,IHC-F,IF,Flow-Cyt,ICC/IF | Bioss

Rrmab?兔单抗
2026-03-02~2026-04-30,KXJ2603
PEN2 Recombinant Rabbit mAb (一抗) - WB,IHC-P,IHC-F,IF,Flow-Cyt,ICC/IF | Bioss
货号:bsm-61979R
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概述

产品编号
bsm-61979R
产品类型
重组兔单抗
英文名称
PEN2 Recombinant Rabbit mAb
中文名称
早老素γ分泌酶2重组兔单抗
英文别名
ACNINV2; MDS033; MSTP064; PEN-2; PEN2; 1700023M09Rik; RGD1312037; PEN2_HUMAN; PSENEN; Presenilin enhancer protein 2; PEN2_MOUSE; PSN2_RAT; Psen2; PS-2; 3.4.23.-; Ps2; Psnl2; PEN2_RAT; Liver regeneration-related protein LRRGT00140;
抗体来源
Rabbit
免疫原
A synthesized peptide derived from human PEN 2: 1-50/101
亚型
IgG
性状
Liquid
纯化方法
affinity purified by Protein A
克隆类型
Recombinant
克隆号
3D19
理论分子量
12 kDa
检测分子量
13 kDa
储存液
10mM phosphate buffered saline(pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol.
SWISS
Gene ID
保存条件
Store at 4℃ for short term. Store at -20℃ for long term. Avoid repeated freeze/thaw cycles.
注意事项
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
背景资料
Essential subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors and APP.The gamma-secretase complex plays a role in Notch and Wnt signaling cascades and regulation of downstream processes via its role in processing key regulatory proteins, and by regulating cytosolic CTNNB1 levels (Probable). PSENEN modulates both endoproteolysis of presenilin and gamma-secretase activity.
早老素γ分泌酶2重组兔单抗-bsm-61979R早老素γ分泌酶2重组兔单抗-bsm-61979R早老素γ分泌酶2重组兔单抗-bsm-61979R

产品应用

应用已检合格种属预测种属推荐稀释比例
WBHuman, Mouse, Rat1:500-2000
IHC-PHumanMouse, Rat1:100-200
IHC-FHumanMouse, Rat1:100-200
IFHumanMouse, Rat1:100-200
Flow-CytHuman, Mouse, Rat1:50-100
ICC/IFHuman, Mouse, Rat1:50-200

交叉反应

交叉反应: Human, Mouse, Rat

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靶标

基因名
PSENEN
蛋白名
gamma-secretase subunit PEN-2
亚基
Component of the gamma-secretase complex, a complex composed of a presenilin homodimer (PSEN1 or PSEN2), nicastrin (NCSTN), APH1 (APH1A or APH1B) and PSENEN/PEN2. Such minimal complex is sufficient for secretase activity, although other components may exist.
亚细胞定位
Endoplasmic reticulum membrane. Golgi apparatus > Golgi stack membrane. Predominantly located in the endoplasmic reticulum and in the cis-Golgi.
组织特异性
Widely expressed. Expressed in leukocytes, lung, placenta, small intestine, liver, kidney, spleen thymus, skeletal muscle, heart and brain.
相似性
Belongs to the PEN-2 family.

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