CTBP1 Recombinant Rabbit mAb (一抗) - WB,IHC-P,IHC-F,IF,Flow-Cyt,ICC/IF,IP | Bioss
Rrmab?兔单抗
货号：bsm-61953R
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概述
产品编号
bsm-61953R
产品类型
重组兔单抗
英文名称
CTBP1 Recombinant Rabbit mAb
中文名称
C端结合蛋白1重组兔单抗
英文别名
BARS; HADDTS; CtBP3/BARS; D4S115h; D5H4S115; D5H4S115E; 50-kDaBFA-inducedADP-ribosylatedsubstrate; BARS-50; CTBP1_HUMAN; CTBP1; 1.1.1.-; CTBP; CTBP1_MOUSE; CTBP1_RAT; 50 kDa BFA-dependent ADP-ribosylation substrate; C-terminal-binding protein 3 (CtBP3); Ctbp3;
抗体来源
Rabbit
免疫原
A synthesized peptide derived from human CtBP1: 350-400/440
亚型
IgG
性状
Liquid
纯化方法
affinity purified by Protein A
克隆类型
Recombinant
克隆号
4B6
理论分子量
48 kDa
检测分子量
45 kDa
储存液
10mM phosphate buffered saline(pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol.
研究领域
Cancer > Cell cycle > Cell cycle inhibitors
Cell Biology > Cell Cycle > Cell Cycle Inhibitors
Epigenetics and Nuclear Signaling > Transcription > Co-factors
Epigenetics and Nuclear Signaling > Transcription > Other factors
Microbiology > Interspecies Interaction > Host Virus Interaction
Microbiology > Organism > Virus > DNA Virus > double stranded DNA Virus > Adenovirus
SWISS
Gene ID
保存条件
Store at 4℃ for short term. Store at -20℃ for long term. Avoid repeated freeze/thaw cycles.
注意事项
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
数据库链接
产品介绍
转录调节因子（Transcriptin Regulators）
背景资料
Corepressor targeting diverse transcription regulators such as GLIS2 or BCL6. Has dehydrogenase activity. Involved in controlling the equilibrium between tubular and stacked structures in the Golgi complex. Functions in brown adipose tissue (BAT) differentiation.
产品应用
| 应用 | 已检合格种属 | 预测种属 | 推荐稀释比例 |
|---|---|---|---|
| WB | Human | Mouse, Rat | 1:500-2000 |
| IHC-P | Human, Mouse, Rat | 1:100-500 | |
| IHC-F | Human, Mouse, Rat | 1:100-500 | |
| IF | Human, Mouse, Rat | 1:100-500 | |
| Flow-Cyt | Human | Mouse, Rat | 1:50-100 |
| ICC/IF | Human, Mouse, Rat | 1:50-200 | |
| IP | Human, Mouse, Rat | 1:20-50 |
交叉反应
交叉反应: Human, Mouse, Rat
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暂无相关产品
靶标
基因名
CTBP1
蛋白名
C-terminal-binding protein 1
亚基
Homo- or heterodimer. Heterodimer with CTBP2. Interacts with PRDM16; the interaction represses white adipose tissue (WAT)-specific genes expression. Interacts with GLIS2, FOXP2, HDAC4, HDAC5, HDAC9 and ZNF217. Interacts with adenovirus E1A protein (via its C-terminus); the interaction disrupts the interaction of CTBP1 with RBBP8. Interacts with Epstein-Barr virus EBNA3 and EBNA6. Interacts with ELK3 (via its PXDLS motif). Interacts with RBBP8 (via its PXDLS motif); the interaction is disrupted by binding to adenovirus E1A. Interacts with FOXP1, HIPK2, PNN, NRIP1, MECOM, ZNF366, ZFHX1B and WIZ. Interaction with SATB1 (non-acetylated form); the interaction stabilizes its attachment to DNA and promotes transcription repression.
亚细胞定位
Cytoplasm. Nucleus.
翻译后修饰
The level of phosphorylation appears to be regulated during the cell cycle. Phosphorylation by HIPK2 on Ser-422 induces proteasomal degradation.
ADP-ribosylated; when cells are exposed to brefeldin A.
Sumoylation on Lys-428 is promoted by the E3 SUMO-protein ligase CBX4.
ADP-ribosylated; when cells are exposed to brefeldin A.
Sumoylation on Lys-428 is promoted by the E3 SUMO-protein ligase CBX4.
相似性
Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
功能
Involved in controlling the equilibrium between tubular and stacked structures in the Golgi complex. Functions in brown adipose tissue (BAT) differentiation. Corepressor targeting diverse transcription regulators such as GLIS2. Has dehydrogenase activity.
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