铁调节蛋白2重组兔单抗
Rrmab®兔单抗
货号：bsm-61944R
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概述
产品编号
bsm-61944R
产品类型
重组兔单抗、mIHC精品抗体
英文名称
Aconitase 2 Recombinant Rabbit mAb
中文名称
铁调节蛋白2重组兔单抗
英文别名
ACONM; HEL-S-284; ICRD; OCA8; OPA9; ACON_HUMAN; ACO2; Aconitase; Citrate hydro-lyase; 4.2.1.3;
抗体来源
Rabbit
免疫原
A synthesized peptide derived from human Aconitase 2: 50-98/780
亚型
IgG
性状
Liquid
纯化方法
affinity purified by Protein A
克隆类型
Recombinant
克隆号
8G6
理论分子量
85
检测分子量
85
储存液
10mM phosphate buffered saline(pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol.
研究领域
Metabolism > Pathways and Processes > Metabolic signaling pathways > Energy transfer pathways > Energy Metabolism
Metabolism > Pathways and Processes > Mitochondrial Metabolism > Mitochondrial markers
Signal Transduction > Metabolism > Energy Metabolism
Signal Transduction > Metabolism > Mitochondrial
Tags & Cell Markers > Subcellular Markers > Organelles > Mitochondria
SWISS
Gene ID
保存条件
Store at 4℃ for short term. Store at -20℃ for long term. Avoid repeated freeze/thaw cycles.
注意事项
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
背景资料
Catalyzes the isomerization of citrate to isocitrate via cis-aconitate.
产品应用
| 应用 | 已检合格种属 | 预测种属 | 推荐稀释比例 |
|---|---|---|---|
| WB | Human, Mouse, Rat | 1:500-2000 | |
| IHC-P | Human, Mouse, Rat | 1:50-200 | |
| IHC-F | Human, Mouse, Rat | 1:50-200 | |
| IF | Human, Mouse, Rat | 1:50-200 | |
| ICC/IF | Human, Mouse, Rat | 1:50-200 | |
| IP | Human, Mouse, Rat | 1:20-50 |
交叉反应
交叉反应: Human, Mouse, Rat
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靶标
基因名
ACO2
蛋白名
Aconitate hydratase, mitochondrial
亚基
Monomer.
亚细胞定位
Mitochondrion.
疾病
Infantile cerebellar-retinal degeneration (ICRD) [MIM:614559]: A severe autosomal recessive neurodegenerative disorder characterized by onset between ages 2 and 6 months of truncal hypotonia, athetosis, seizures, and ophthalmologic abnormalities, particularly optic atrophy and retinal degeneration. Affected individuals show profound psychomotor retardation, with only some achieving rolling, sitting, or recognition of family. Brain MRI shows progressive cerebral and cerebellar degeneration. Note=The disease is caused by mutations affecting the gene represented in this entry.
相似性
Belongs to the aconitase/IPM isomerase family.
功能
Catalyzes the isomerization of citrate to isocitrate via cis-aconitate.
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