白细胞介素增强子结合因子3重组兔单抗
Rrmab®兔单抗
货号：bsm-61910R
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概述
产品编号
bsm-61910R
产品类型
重组兔单抗、mIHC精品抗体
英文名称
ILF3 Recombinant Rabbit mAb
中文名称
白细胞介素增强子结合因子3重组兔单抗
英文别名
CBTF; DRBF; DRBP76; MMP4; MPHOSPH4; MPP4; MPP4110; NF-AT-90; NF110; NF110b; NF90; NF90a; NF90b; NF90c; NF90ctv; NFAR; NFAR-1; NFAR-2; NFAR110; NFAR2; NFAR90; TCP110; TCP80; MBII-26; ilf3; wu:fb37d07; wu:fb94b02; zgc:77030; ILF3_HUMAN; Double-stranded RNA-binding protein 76 (DRBP76); M-phase phosphoprotein 4 (MPP4); Nuclear factor associated with dsRNA (NFAR); Nuclear factor of activated T-cells 90 kDa (NF-AT-90); Translational control protein 80 (TCP80); ILF3_MOUSE; ILF3_RAT; ILF3_DANRE;
抗体来源
Rabbit
免疫原
A synthesized peptide derived from human ILF3: 1-50/894
亚型
IgG
性状
Liquid
纯化方法
affinity purified by Protein A
克隆类型
Recombinant
克隆号
12B4
理论分子量
95
检测分子量
95,110
储存液
10mM phosphate buffered saline(pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol.
研究领域
SWISS
Gene ID
保存条件
Store at 4℃ for short term. Store at -20℃ for long term. Avoid repeated freeze/thaw cycles.
注意事项
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
背景资料
May facilitate double-stranded RNA-regulated gene expression at the level of post-transcription. Can act as a translation inhibitory protein which binds to coding sequences of acid beta-glucosidase (GCase) and other mRNAs and functions at the initiation phase of GCase mRNA translation, probably by inhibiting its binding to polysomes.
产品应用
| 应用 | 已检合格种属 | 预测种属 | 推荐稀释比例 |
|---|---|---|---|
| WB | Human | Mouse | 1:500-2000 |
| IHC-P | Human, Mouse | 1:100-500 | |
| IHC-F | Human, Mouse | 1:100-500 | |
| IF | Human, Mouse | 1:100-500 | |
| Flow-Cyt | Human | Mouse, Rat | 1:50-100 |
| ICC/IF | Human, Mouse | 1:50-200 | |
| IP | Human, Mouse | 1:20-50 |
交叉反应
交叉反应: Human, Mouse
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靶标
基因名
ILF3
蛋白名
Interleukin enhancer-binding factor 3
亚细胞定位
Nucleus; nucleolus. Cytoplasm. Localized in cytoplasmic mRNP granules containing untranslated mRNAs.
组织特异性
Ubiquitous.
翻译后修饰
Phosphorylated by RNA-dependent protein kinase (EIF2AK2).
Methylated by protein arginine N-methyltransferase 1.
Arg-609 is dimethylated, probably to asymmetric dimethylarginine.
Methylated by protein arginine N-methyltransferase 1.
Arg-609 is dimethylated, probably to asymmetric dimethylarginine.
相似性
Contains 2 DRBM (double-stranded RNA-binding) domains.
Contains 1 DZF domain.
Contains 1 DZF domain.
功能
May facilitate double-stranded RNA-regulated gene expression at the level of post-transcription. Can act as a translation inhibitory protein which binds to coding sequences of acid beta-glucosidase (GCase) and other mRNAs and functions at the initiation phase of GCase mRNA translation, probably by inhibiting its binding to polysomes. Can regulate protein arginine N-methyltransferase 1 activity. May regulate transcription of the IL2 gene during T-cell activation. Can promote the formation of stable DNA-dependent protein kinase holoenzyme complexes on DNA.
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