FNDC5重组兔单抗

Rrmab®兔单抗
2026-01-04~2026-02-28,RR26012026-01-04~2026-02-28,TR
FNDC5重组兔单抗
货号:bsm-61901R
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概述

产品编号
bsm-61901R
产品类型
重组兔单抗
英文名称
FNDC5 Recombinant Rabbit mAb
中文名称
FNDC5重组兔单抗
英文别名
FRCP2; irisin; 1500001L03Rik; PeP; Pxp; FNDC5_HUMAN; FNDC5; Fibronectin type III repeat-containing protein 2; FNDC5_MOUSE; Peroxisomal protein (PeP); FNDC5_RAT;
抗体来源
Rabbit
免疫原
A synthesized peptide derived from human FNDC5: 50-100/212
亚型
IgG
性状
Liquid
纯化方法
affinity purified by Protein A
克隆类型
Recombinant
克隆号
5B5
理论分子量
24
检测分子量
24
储存液
10mM phosphate buffered saline(pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol.
SWISS
Gene ID
保存条件
Store at 4℃ for short term. Store at -20℃ for long term. Avoid repeated freeze/thaw cycles.
注意事项
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
背景资料
Contrary to mouse, may not be involved in the beneficial effects of muscular exercise, nor in the induction of browning of human white adipose tissue.
FNDC5重组兔单抗

产品应用

应用已检合格种属预测种属推荐稀释比例
WBMouse, RatHuman1:500-2000

交叉反应

交叉反应: Human, Mouse, Rat

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靶标

基因名
FNDC5
蛋白名
Fibronectin type III domain-containing protein 5
亚细胞定位
Cell membrane; Single-pass type I membrane protein. Peroxisome membrane; Single-pass type I membrane protein. Note=Imported in peroxisomes through the PEX5 receptor pathway.
Irisin: Secreted. Note=Detected in the blood of individuals subjected to endurance exercise.
翻译后修饰
The extracellular domain is cleaved and released from the cell membrane.
N-Glycosylated.
相似性
Contains 1 fibronectin type-III domain.
功能
Irisin: mediates beneficial effects of muscular exercise. Induces browning of white adipose tissue by stimulating UCP1 expression, at least in part, via the nuclear receptor PPARA.

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