Gephyrin Recombinant Rabbit mAb (一抗) - WB | Bioss
Rrmab?兔单抗
货号：bsm-61891R
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概述
产品编号
bsm-61891R
产品类型
重组兔单抗
英文名称
Gephyrin Recombinant Rabbit mAb
中文名称
桥尾蛋白重组兔单抗
英文别名
GEPH; GPH; GPHRYN; HKPX1; MOCODC; 5730552E08Rik; C230040D23; GEPH_HUMAN; GPHN; KIAA1385; GEPH_MOUSE; GEPH_RAT; Putative glycine receptor-tubulin linker protein; gephyrin
抗体来源
Rabbit
免疫原
A synthesized peptide derived from human Gephyrin: 1-54/736
亚型
IgG
性状
Liquid
纯化方法
affinity purified by Protein A
克隆类型
Recombinant
克隆号
6B3
理论分子量
80 kDa
检测分子量
95 kDa
储存液
10mM phosphate buffered saline(pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol.
研究领域
SWISS
Gene ID
保存条件
Store at 4℃ for short term. Store at -20℃ for long term. Avoid repeated freeze/thaw cycles.
注意事项
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
数据库链接
背景资料
Microtubule-associated protein involved in membrane protein-cytoskeleton interactions. It is thought to anchor the inhibitory glycine receptor (GLYR) to subsynaptic microtubules.
产品应用
| 应用 | 已检合格种属 | 预测种属 | 推荐稀释比例 |
|---|---|---|---|
| WB | Human | Mouse, Rat | 1:500-2000 |
交叉反应
交叉反应: Human (predicted: Mouse, Rat)
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靶标
基因名
GPHN
蛋白名
Gephyrin
亚基
Homotrimer. Interacts with GABARAP (By similarity).
亚细胞定位
Cell junction, synapse (By similarity). Cell junction, synapse, postsynaptic cell membrane; Peripheral membrane protein; Cytoplasmic side (By similarity). Cytoplasm, cytoskeleton (By similarity). Note=Cytoplasmic face of glycinergic postsynaptic membranes (By similarity).
疾病
Defects in GPHN are the cause of molybdenum cofactor deficiency type C (MOCOD type C) [MIM:252150]. MOCOD type C is an autosomal recessive disease which leads to the pleiotropic loss of all molybdoenzyme activities and is characterized by severe neurological damage, neonatal seizures and early childhood death.
相似性
In the N-terminal section; belongs to the moaB/mog family.
In the C-terminal section; belongs to the moeA family.
In the C-terminal section; belongs to the moeA family.
功能
Microtubule-associated protein involved in membrane protein-cytoskeleton interactions. It is thought to anchor the inhibitory glycine receptor (GLYR) to subsynaptic microtubules (By similarity). Catalyzes two steps in the biosynthesis of the molybdenum cofactor. In the first step, molybdopterin is adenylated. Subsequently, molybdate is inserted into adenylated molybdopterin and AMP is released.
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