PSMD4 | RPN10/S5A Recombinant Rabbit mAb (一抗) - WB,IHC-P,IHC-F,IF,Flow-Cyt,ICC/IF,IP | Bioss

bsm-61859R

重组兔单抗

PSMD4 | RPN10/S5A Recombinant Rabbit mAb

26S蛋白酶调节亚型S5a重组兔单抗

AF; AF-1; ASF; MCB1; Rpn10; S5A; pUB-R5; Af1; angiocidin; PSMD4_HUMAN; PSMD4; 26S proteasome regulatory subunit RPN10; 26S proteasome regulatory subunit S5A; Antisecretory factor 1 (AF | ASF); Multiubiquitin chain-binding protein; PSMD4_MOUSE; proteasome 26S subunit ubiquitin receptor, non-ATPase 4; proteasome (prosome, macropain) 26S subunit, non-ATPase, 4; proteasome 26S subunit, non-ATPase 4

Rabbit

A synthesized peptide derived from human PSMD4: 310-377/377

IgG

Liquid

affinity purified by Protein A

Recombinant

9H12

41 kDa

50 kDa

0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.

This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

Binds and presumably selects ubiquitin-conjugates for destruction. Displays selectivity for longer polyubiquitin chains. Modulates intestinal fluid secretion.

PSMD4

26S proteasome non-ATPase regulatory subunit 4

The 26S proteasome is composed of a core protease, known as the 20S proteasome, capped at one or both ends by the 19S regulatory complex (RC). The RC is composed of at least 18 different subunits in two subcomplexes, the base and the lid, which form the portions proximal and distal to the 20S proteolytic core, respectively. Directly interacts with NUB1. Interacts with SQSTM1. Interacts with UBQLN4. Interacts with UBE3A.

Phosphorylated upon DNA damage, probably by ATM or ATR.

Belongs to the proteasome subunit S5A family.
Contains 2 UIM (ubiquitin-interacting motif) repeats.
Contains 1 VWFA domain.

Binds and presumably selects ubiquitin-conjugates for destruction. Displays selectivity for longer polyubiquitin chains. Modulates intestinal fluid secretion.