谷胱甘肽合成酶重组兔单抗

Rrmab®兔单抗
2026-01-04~2026-02-28,RR26012026-01-04~2026-02-28,TR
谷胱甘肽合成酶重组兔单抗
货号:bsm-61855R
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概述

产品编号
bsm-61855R
产品类型
重组兔单抗
英文名称
Glutathione synthetase Recombinant Rabbit mAb
中文名称
谷胱甘肽合成酶重组兔单抗
英文别名
CNSHA6; GSHS; HEL-S-64p; HEL-S-88n; GS-A/GS-B; GSH-S; GSHB_HUMAN; GSS; GSH synthetase; Glutathione synthase; 6.3.2.3; GSHB_MOUSE; GSHB_RAT;
抗体来源
Rabbit
免疫原
A synthesized peptide derived from human GSS: 321-400
亚型
IgG
性状
Liquid
纯化方法
affinity purified by Protein A
克隆类型
Recombinant
克隆号
3H3
理论分子量
52
检测分子量
52
储存液
10mM phosphate buffered saline(pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol.
SWISS
Gene ID
保存条件
Store at 4℃ for short term. Store at -20℃ for long term. Avoid repeated freeze/thaw cycles.
注意事项
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
背景资料
Catalyzes the production of glutathione from gamma-glutamylcysteine and glycine in an ATP-dependent manner.Glutathione (gamma-glutamylcysteinylglycine, GSH) is the most abundant intracellular thiol in living aerobic cells and is required for numerous processes including the protection of cells against oxidative damage, amino acid transport, the detoxification of foreign compounds, the maintenance of protein sulfhydryl groups in a reduced state and acts as a cofactor for a number of enzymes.
谷胱甘肽合成酶重组兔单抗

产品应用

应用已检合格种属预测种属推荐稀释比例
WBHuman, Mouse, Rat1:500-2000
Flow-CytHuman, Mouse, Rat1:50-100
ICC/IFHuman, Mouse, Rat1:50-200

交叉反应

交叉反应: Human, Mouse, Rat

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靶标

基因名
GSS
蛋白名
Glutathione synthetase
亚基
Homodimer.
亚细胞定位
Cytosol
疾病
Defects in GSS are the cause of glutathione synthetase deficiency (GSS deficiency) [MIM:266130]; also known as 5-oxoprolinuria or pyroglutamic aciduria. It is a severe form characterized by an increased rate of hemolysis and defective function of the central nervous system.
Defects in GSS are the cause of glutathione synthetase deficiency of erythrocytes (GLUSYNDE)[MIM:231900]. Glutathione synthetase deficiency of erythrocytes is a mild form causing hemolytic anemia.
相似性
Belongs to the eukaryotic GSH synthase family.
功能
Sulfur metabolism; glutathione biosynthesis; glutathione from L-cysteine and L-glutamate: step 2/2.

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