肝羧酸酯酶1重组兔单抗

Rrmab®兔单抗
2026-01-04~2026-02-28,RR26012026-01-04~2026-02-28,TR
肝羧酸酯酶1重组兔单抗
货号:bsm-61827R
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概述

产品编号
bsm-61827R
产品类型
重组兔单抗
英文名称
CES1 Recombinant Rabbit mAb
中文名称
肝羧酸酯酶1重组兔单抗
英文别名
ACAT; CE-1; CEH; CES2; HMSE; HMSE1; PCE-1; REH; SES1; TGH; hCE-1; Ces-1; Ces1; Ses-1; Es1; Es2; Es22; EST1_HUMAN; Acyl-coenzyme A:cholesterol acyltransferase (ACAT); Brain carboxylesterase hBr1; Carboxylesterase 1 (CE-1 | hCE-1); Cholesteryl ester hydrolase (CEH); Cocaine carboxylesterase; Egasyn; Methylumbelliferyl-acetate deacetylase 1; Monocyte/macrophage serine esterase; Retinyl ester hydrolase (REH); Serine esterase 1; Triacylglycerol hydrolase (TGH); EST1_MOUSE; Acyl-coenzyme A:cholesterol acyltransferase; Carboxylesterase 1G; ES-x; 3.1.1.1; Ces1g; EST1C_RAT; Ces1c; Carboxyesterase ES-1 (E1); ES-THET; Esterase-2; Liver carboxylesterase 1; Neutral retinyl ester hydrolase (NREH); EST1E_RAT; Ces1e; Carboxyesterase ES-3; ES-HTEL; Liver carboxylesterase 3; pI 5.5 esterase;
抗体来源
Rabbit
免疫原
A synthesized peptide derived from human CES1: 64-82
亚型
IgG
性状
Liquid
纯化方法
affinity purified by Protein A
克隆类型
Recombinant
克隆号
13E4
理论分子量
63
检测分子量
55
储存液
10mM phosphate buffered saline(pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol.
SWISS
Gene ID
保存条件
Store at 4℃ for short term. Store at -20℃ for long term. Avoid repeated freeze/thaw cycles.
注意事项
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
背景资料
Involved in the detoxification of xenobiotics and in the activation of ester and amide prodrugs. Hydrolyzes aromatic and aliphatic esters, but has no catalytic activity toward amides or a fatty acyl-CoA ester. Hydrolyzes the methyl ester group of cocaine to form benzoylecgonine.
肝羧酸酯酶1重组兔单抗

产品应用

应用已检合格种属预测种属推荐稀释比例
WBHuman, Mouse, Rat1:500-2000
Flow-CytHuman, Mouse, Rat1:50-100
IPHuman, Mouse, Rat1:20-50

交叉反应

交叉反应: Human, Mouse, Rat

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靶标

基因名
Ces1
蛋白名
Liver carboxylesterase 1
亚细胞定位
Endoplasmic reticulum lumen.
组织特异性
Expressed predominantly in liver with lower levels in heart and lung.
翻译后修饰
Contains sialic acid.
Cleavage of the signal sequence can occur at 2 positions, either between Trp-17 and Gly-18 or between Gly-18 and His-19.
相似性
Belongs to the type-B carboxylesterase/lipase family.
功能
Involved in the detoxification of xenobiotics and in the activation of ester and amide prodrugs. Hydrolyzes aromatic and aliphatic esters, but has no catalytic activity toward amides or a fatty acyl-CoA ester. Hydrolyzes the methyl ester group of cocaine to form benzoylecgonine. Catalyzes the transesterification of cocaine to form cocaethylene. Displays fatty acid ethyl ester synthase activity, catalyzing the ethyl esterification of oleic acid to ethyloleate.

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