Creatine kinase B type Recombinant Rabbit mAb (一抗) - WB,IHC-P,IHC-F,IF,Flow-Cyt,ICC/IF,IP | Bioss

bsm-61776R

重组兔单抗

Creatine kinase B type Recombinant Rabbit mAb

脑型肌酸激酶B型重组兔单抗

B-CK; BCK; CKBB; CPK-B; HEL-211; HEL-S-29; CKMM; CPK-M; M-CK; KCRM_HUMAN; CKM; Creatine kinase M chain; Creatine phosphokinase M-type (CPK-M); 2.7.3.2; KCRB_HUMAN; CKB; Brain creatine kinase (B-CK); Creatine kinase B chain; Creatine phosphokinase B-type (CPK-B); creatine kinase B; creatine kinase, brain; creatine kinase brain-type

Rabbit

A synthesized peptide derived from human Creatine kinase B type: 50-100/381

IgG

Liquid

affinity purified by Protein A

Recombinant

10G4

43 kDa

42 kDa

10mM phosphate buffered saline(pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol.

Store at 4℃ for short term. Store at -20℃ for long term. Avoid repeated freeze/thaw cycles.

This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

Reversibly catalyzes the transfer of phosphate between ATP and various phosphogens (e.g. creatine phosphate). Creatine kinase isoenzymes play a central role in energy transduction in tissues with large, fluctuating energy demands, such as skeletal muscle, heart, brain and spermatozoa (Probable). Acts as a key regulator of adaptive thermogenesis as part of the futile creatine cycle: localizes to the mitochondria of thermogenic fat cells and acts by mediating phosphorylation of creatine to initiate a futile cycle of creatine phosphorylation and dephosphorylation.

CKB

Creatine kinase B-type

Dimer of identical or non-identical chains. With MM being the major form in skeletal muscle and myocardium, MB existing in myocardium, and BB existing in many tissues, especially brain.

Cytoplasmic and Mitochondrial

Belongs to the ATP:guanido phosphotransferase family.
Contains 1 phosphagen kinase C-terminal domain.
Contains 1 phosphagen kinase N-terminal domain.

Creatine Kinase MB consists of a dimer of nonidentical chains. With MM being the major form in skeletal muscle and myocardium, MB existing in myocardium, and BB existing in many tissues, especially brain. Creatine Kinase MB reversibly catalyses the transfer of phosphate between ATP and various phosphogens. The creatine kinase isoenzymes play a central role in energy transduction in tissues with large fluctuating energy demands such as skeletal muscle, heart, brain and spermatozoa.