Prostate Secretory Protein/PSP Recombinant Rabbit mAb (一抗) - WB,IHC-P,IHC-F,IF,IP | Bioss

bsm-61761R

重组兔单抗

Prostate Secretory Protein/PSP Recombinant Rabbit mAb

前列腺分泌蛋白重组兔单抗

HPC13; IGBF; MSP; MSPB; PN44; PRPS; PSP; PSP-94; PSP57; PSP94; MSMB_HUMAN; MSMB; Immunoglobulin-binding factor (IGBF); Prostate secreted seminal plasma protein; Prostate secretory protein of 94 amino acids (PSP-94 | PSP94); Seminal plasma beta-inhibin; PRSP; microseminoprotein beta; microseminoprotein, beta-; beta-microseminoprotein

Rabbit

A synthesized peptide derived from human beta 2 Microseminoprotein: 2-52/114

IgG

Liquid

affinity purified by Protein A

Recombinant

8D3

13 kDa

15 kDa

10mM phosphate buffered saline(pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol.

Store at 4℃ for short term. Store at -20℃ for long term. Avoid repeated freeze/thaw cycles.

This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

The protein encoded by this gene is a member of the immunoglobulin binding factor family. It is synthesized by the epithelial cells of the prostate gland and secreted into the seminal plasma. This protein has inhibin-like activity. It may have a role as an autocrine paracrine factor in uterine, breast and other female reproductive tissues. The expression of the encoded protein is found to be decreased in prostate cancer.

MSMB

beta-microseminoprotein

Secreted. Sperm surface.

Strongly expressed in prostate, liver, kidney, breast and penis. Also expressed in pancreas, esophagus, stomach, deodenum, colon, trachea, lung, salivary glands and fallopian tube. PSP94 is expressed in lung and breast, whereas PSP57 is found in kidney and bladder.

Defects in MSMB are the cause of susceptibility to prostate cancer hereditary type 13 (HPC13) [MIM:611928]. It is a condition associated with familial predisposition to cancer of the prostate. Most prostate cancers are adenocarcinomas that develop in the acini of the prostatic ducts. Other rare histopathologic types of prostate cancer that occur in approximately 5% of patients include small cell carcinoma, mucinous carcinoma, prostatic ductal carcinoma, transitional cell carcinoma, squamous cell carcinoma, basal cell carcinoma, adenoid cystic carcinoma (basaloid), signet-ring cell carcinoma and neuroendocrine carcinoma.

Belongs to the beta-microseminoprotein family.