IGFBP7 Recombinant Rabbit mAb (一抗) - WB,IHC-P,IHC-F,IF,Flow-Cyt,ICC/IF | Bioss

bsm-61734R

重组兔单抗

IGFBP7 Recombinant Rabbit mAb

胰岛素样生长因子结合蛋白7重组兔单抗

AGM; FSTL2; IBP-7; IGFBP-7; IGFBP-7v; IGFBPRP1; MAC25; PSF; RAMSVPS; TAF; IGFBP-RP-1; IGFBP-rP1; IBP7_HUMAN; IGFBP7; IGF-binding protein 7; MAC25 protein; PGI2-stimulating factor; Prostacyclin-stimulating factor; Tumor-derived adhesion factor (TAF); IBP7_MOUSE; insulin like growth factor binding protein 7; insulin-like growth factor binding protein 7

Rabbit

A synthesized peptide derived from human IBP 7: 100-200

IgG

Liquid

affinity purified by Protein A

Recombinant

12A15

29 kDa

32 kDa

0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Store at 4℃ for short term. Store at -20℃ for long term. Avoid repeated freeze/thaw cycles.

This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

Binds IGF-I and IGF-II with a relatively low affinity. Stimulates prostacyclin (PGI2) production. Stimulates cell adhesion.

IGFBP7

Insulin-like growth factor-binding protein 7

May interact with VPS24/CHMP3; the relevance of such interaction however remains unclear.

Secreted.

N-glycosylated.

Defects in IGFBP7 are the cause of retinal arterial macroaneurysm with supravalvular pulmonic stenosis (RAMSVPS) [MIM:614224]. RAMSVPS is an autosomal recessive condition characterized by the bilateral appearance of 'beading' along the major retinal arterial trunks, with the subsequent formation of macroaneurysms. Affected individuals also have supravalvular pulmonic stenosis, often requiring surgical correction.

Contains 1 Ig-like C2-type (immunoglobulin-like) domain.Contains 1 IGFBP N-terminal domain.Contains 1 Kazal-like domain.