过氧化物酶体增殖物激活受体γ辅激活子1β重组兔单抗

Rrmab®兔单抗
2026-01-04~2026-02-28，RR26012026-01-04~2026-02-28，TR
一键复制 说明书
过氧化物酶体增殖物激活受体γ辅激活子1β重组兔单抗
货号：bsm-61701R
产品详情
相关标记
相关产品
相关文献
常见问题

概述

产品编号
bsm-61701R
产品类型
重组兔单抗
英文名称
PGC1 beta Recombinant Rabbit mAb
中文名称
过氧化物酶体增殖物激活受体γ辅激活子1β重组兔单抗
英文别名
ERRL1; PERC; PGC-1(beta); PGC1B; PRGC2_HUMAN; PPARGC1B; PGC-1-beta; PPAR-gamma coactivator 1-beta; PPARGC-1-beta; PGC-1-related estrogen receptor alpha coactivator; PGC1; PPARGC1; 4631412G21Rik; PGC-1beta; PGC-1beta/ERRL1; PGC1beta; PRGC2_MOUSE; ERR ligand 1; PRGC2_RAT;
抗体来源
Rabbit
免疫原
A synthesized peptide derived from human PGC1 beta: 970-1023
亚型
IgG
性状
Liquid
纯化方法
affinity purified by Protein A
克隆类型
Recombinant
克隆号
19E18
理论分子量
113
检测分子量
113
储存液
10mM phosphate buffered saline(pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol.
研究领域

Cardiovascular > Atherosclerosis > Diabetes associated

Cardiovascular > Lipids / Lipoproteins > Fatty Acids > Metabolism

Epigenetics and Nuclear Signaling > Nuclear Signaling Pathways > Nuclear Receptors > Co-activators/co-repressors

Epigenetics and Nuclear Signaling > Nuclear Signaling Pathways > Nuclear Receptors > Estrogen

Metabolism > Pathways and Processes > Metabolic signaling pathways > Energy transfer pathways > Energy Metabolism

Metabolism > Pathways and Processes > Metabolic signaling pathways > Lipid and lipoprotein metabolism > Fatty acids

Metabolism > Pathways and Processes > Mitochondrial Metabolism > Mitochondrial markers

Metabolism > Pathways and Processes > Redox metabolism > Fatty acid oxidation

Metabolism > Types of disease > Diabetes

Metabolism > Types of disease > Heart disease

Signal Transduction > Metabolism > Energy Metabolism

Signal Transduction > Metabolism > Mitochondrial

SWISS
Q86YN6
Gene ID
133522
保存条件
Store at 4℃ for short term. Store at -20℃ for long term. Avoid repeated freeze/thaw cycles.
注意事项
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
数据库链接

Entrez Gene : 133522 Human

SwissProt : Q86YN6 Human

Entrez Gene : 170826 Mouse

Entrez Gene : 291567 Rat

SwissProt : Q8VHJ7 Mouse

SwissProt : Q811R2 Rat

背景资料
Plays a role of stimulator of transcription factors and nuclear receptors activities. Activates transcriptional activity of estrogen receptor alpha, nuclear respiratory factor 1 (NRF1) and glucocorticoid receptor in the presence of glucocorticoids. May play a role in constitutive non-adrenergic-mediated mitochondrial biogenesis as suggested by increased basal oxygen consumption and mitochondrial number when overexpressed.
过氧化物酶体增殖物激活受体γ辅激活子1β重组兔单抗

产品应用

应用已检合格种属预测种属推荐稀释比例
WBHuman, Mouse, Rat1:500-2000
IPHuman, Mouse, Rat1:20-50

交叉反应

交叉反应: Human, Mouse, Rat

相关产品

暂无相关产品

靶标

基因名
PPARGC1B
蛋白名
Peroxisome proliferator-activated receptor gamma coactivator 1-beta
亚基
Interacts with hepatocyte nuclear factor 4-alpha/HNF4A,Sterol regulatory binding transcription factor 1/SREBF1,PPAR-alpha/PPARA, thyroid hormone receptor beta/THRB and host cellfactor/HCFC1. Interacts with estrogen-related receptor gamma/ESRRGand alpha/ESRRA. Interacts with PRDM16 (By similarity). Interactswith estrogen receptor alpha/ESR1.
亚细胞定位
Nucleus.
组织特异性
Ubiquitous with higher expression in heart,brain and skeletal muscle.
相似性
Contains 1 RRM (RNA recognition motif) domain.
功能
Plays a role of stimulator of transcription factors andnuclear receptors activities. Activates transcritional activity ofestrogen receptor alpha, nuclear respiratory factor 1 (NRF1) andglucocorticoid receptor in the presence of glucocorticoids. Mayplay a role in constitutive non-adrenergic-mediated mitochondrialbiogenesis as suggested by increased basal oxygen consumption andmitochondrial number when overexpressed. May be involved in fatoxidation and non-oxidative glucose metabolism and in theregulation of energy expenditure.

标记抗体

暂无标记数据

同靶标产品

暂无同靶标产品

相关文献

提示: 发表研究结果有使用 bsm-61701R 时请让我们知道，以便我们可以引用参考文章。作为回馈，资料提供者将获得我们送上的小礼品。

暂无相关文献

常见问题

暂无常见问题