线粒体转录因子1重组兔单抗
Rrmab®兔单抗
货号：bsm-61684R
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概述
产品编号
bsm-61684R
产品类型
重组兔单抗、mIHC精品抗体
英文名称
MtTF1 Recombinant Rabbit mAb
中文名称
线粒体转录因子1重组兔单抗
英文别名
MTDPS15; MTTF1; MTTFA; TCF6; TCF6L1; TCF6L2; TCF6L3; TFAM_HUMAN; TFAM; Mitochondrial transcription factor 1 (MtTF1); Transcription factor 6 (TCF-6); Transcription factor 6-like 2;
抗体来源
Rabbit
免疫原
A synthesized peptide derived from human mtTFA: 52-80
亚型
IgG
性状
Liquid
纯化方法
affinity purified by Protein A
克隆类型
Recombinant
克隆号
3C11
理论分子量
29
检测分子量
24
储存液
10mM phosphate buffered saline(pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol.
研究领域
Cardiovascular > Heart > Cardiogenesis > Transcription factors/regulators
Epigenetics and Nuclear Signaling > Transcription > Transcription Factors
Metabolism > Pathways and Processes > Metabolic signaling pathways > Nucleotide metabolism > Molecular processes > Mitochondrial transcription
Metabolism > Pathways and Processes > Mitochondrial Metabolism > Mitochondrial Biogenesis
Metabolism > Pathways and Processes > Mitochondrial Metabolism > Mitochondrial markers
Signal Transduction > Metabolism > Mitochondrial
Tags & Cell Markers > Subcellular Markers > Organelles > Mitochondria
SWISS
Gene ID
保存条件
Store at 4℃ for short term. Store at -20℃ for long term. Avoid repeated freeze/thaw cycles.
注意事项
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
数据库链接
背景资料
Binds to the mitochondrial light strand promoter and functions in mitochondrial transcription regulation. Required for accurate and efficient promoter recognition by the mitochondrial RNA polymerase.
产品应用
| 应用 | 已检合格种属 | 预测种属 | 推荐稀释比例 |
|---|---|---|---|
| WB | Human | 1:500-2000 | |
| IHC-P | Human | 1:50-200 | |
| IHC-F | Human | 1:50-200 | |
| IF | Human | 1:50-200 | |
| ICC/IF | Human | 1:50-200 | |
| IP | Human | 1:20-50 |
交叉反应
交叉反应: Human
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靶标
基因名
TFAM
蛋白名
Transcription factor A, mitochondrial
亚细胞定位
Mitochondrion. Mitochondrion matrix, mitochondrion nucleoid.
相似性
Contains 2 HMG box DNA-binding domains.
功能
Binds to the mitochondrial light strand promoter and functions in mitochondrial transcription regulation. Required for accurate and efficient promoter recognition by the mitochondrial RNA polymerase. Promotes transcription initiation from the HSP1 and the light strand promoter by binding immediately upstream of transcriptional start sites. Is able to unwind and bend DNA. Required for maintenance of normal levels of mitochondrial DNA. May play a role in organizing and compacting mitochondrial DNA. Target DNA. Interacts with TFB1M and TFB2M. Associates with mitochondrial DNA.
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