Binds heme and transports it to the liver for breakdown and iron recovery, after which the free hemopexin returns to the circulation.
基因名
HPX
蛋白名
Hemopexin
亚基
Interacts with HEV ORF3 protein. Interacts with FLVCR1.
亚细胞定位
Secreted.
组织特异性
Expressed by the liver and secreted in plasma.
翻译后修饰
N- and O-glycosylated. O-glycosylated with core 1 or possibly core 8 glycans. O-glycosylation in the 30-40 region is minor compared to glycosylation at Thr-24 and Thr-29.
相似性
Belongs to the hemopexin family. Contains 5 hemopexin-like domains.
功能
Binds heme and transports it to the liver for breakdown and iron recovery, after which the free hemopexin returns to the circulation.