LPA1 Recombinant Rabbit mAb (一抗) - IHC-P,IHC-F,IF | Bioss

bsm-61606R

重组兔单抗

LPA1 Recombinant Rabbit mAb

溶血磷脂酸受体蛋白1/EDG2重组兔单抗

EDG2; Gpcr26; LPA1; Mrec1.3; VZG1; edg-2; rec.1.3; vzg-1; Kdt2; LPAR1_BOVIN; LPAR1; LPA receptor 1; LPA-1; Lysophosphatidic acid receptor Edg-2; Rec1.3; LPAR1_HUMAN; LPAR1_MOUSE; LPAR1_RAT; Gpcr91; LPAR1_SHEEP; lysophosphatidic acid receptor 1; endothelial differentiation, lysophosphatidic acid G-protein-coupled receptor, 2

Rabbit

A synthesized peptide derived from human LPA receptor 1: 15-60

IgG

Liquid

affinity purified by Protein A

Recombinant

7C2

41 kDa

39 kDa

10mM phosphate buffered saline(pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol.

Store at 4℃ for short term. Store at -20℃ for long term. Avoid repeated freeze/thaw cycles.

This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

Plays a role in the reorganization of the actin cytoskeleton, cell migration, differentiation and proliferation, and thereby contributes to the responses to tissue damage and infectious agents. Activates downstream signaling cascades via the G(i)/G(o), G12/G13, and G(q) families of heteromeric G proteins. Signaling inhibits adenylyl cyclase activity and decreases cellular cAMP levels.

LPAR1

Lysophosphatidic acid receptor 1

Interacts with RALA and ADRBK1.

Cell surface. Cell membrane; Multi-pass membrane protein. Note=Prior to LPA treatment found predominantly at the cell surface but in the presence of LPA co-localizes with RALA in the endocytic vesicles.

Expressed in many adult organs, including brain, heart, colon, small intestine, placenta, prostate, ovary, pancreas, testes, spleen, skeletal muscle, and kidney. Little or no expression in liver, lung, thymus, or peripheral blood leukocytes.

Belongs to the G-protein coupled receptor 1 family.

Receptor for lysophosphatidic acid (LPA), a mediator of diverse cellular activities. Seems to be coupled to the G(i)/G(o), G(12)/G(13), and G(q) families of heteromeric G proteins. Stimulates phospholipase C (PLC) activity in a manner that is dependent on RALA activation.