硫氧环蛋白还原酶1重组兔单抗

Rrmab®兔单抗
2026-01-04~2026-02-28,RR26012026-01-04~2026-02-28,TR
硫氧环蛋白还原酶1重组兔单抗
货号:bsm-61558R
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概述

产品编号
bsm-61558R
产品类型
重组兔单抗
英文名称
TXNRD1 Recombinant Rabbit mAb
中文名称
硫氧环蛋白还原酶1重组兔单抗
英文别名
GRIM-12; TR; TR1; TRXR1; TXNR; TXNR1; TRXR1_BOVIN; TXNRD1; Peroxidase TXNRD1; Thioredoxin reductase TR1; 1.8.1.9; TRXR1_HUMAN; Gene associated with retinoic and interferon-induced mortality 12 protein (GRIM-12 | Gene associated with retinoic and IFN-induced mortality 12 protein); KM-102-derived reductase-like factor; GRIM12; KDRF; TRXR1_MOUSE; TRXR1_RAT; NADPH-dependent thioredoxin reductase;
抗体来源
Rabbit
免疫原
A synthesized peptide derived from human TR: 1-649/649
亚型
IgG
性状
Liquid
纯化方法
affinity purified by Protein A
克隆类型
Recombinant
克隆号
20F6
理论分子量
71
检测分子量
55
储存液
10mM phosphate buffered saline(pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol.
SWISS
Gene ID
保存条件
Store at 4℃ for short term. Store at -20℃ for long term. Avoid repeated freeze/thaw cycles.
注意事项
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
背景资料
Homodimeric flavoprotein involved in the regulation of cellular redox reactions, growth and differentiation. Contains a selenocysteine residue at the C-terminal active site that is essential for catalysis (Probable). Also has reductase activity on hydrogen peroxide (H2O2).
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产品应用

应用已检合格种属预测种属推荐稀释比例
WBHuman, Mouse, Rat1:1000-5000
IHC-PHuman, Mouse, Rat1:100-500
IHC-FHuman, Mouse, Rat1:100-500
IFHuman, Mouse, Rat1:100-500
Flow-CytHumanMouse, Rat1ug/Test
ICC/IFHumanMouse, Rat1:50-200
IPHuman, Mouse, Rat1:20-50

交叉反应

交叉反应: Human, Mouse, Rat

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靶标

基因名
TXNRD1
蛋白名
Thioredoxin reductase 1, cytoplasmic
亚基
Homodimer. Isoform 4 interacts with ESR1 and ESR2. Interacts with HERC5.
亚细胞定位
Cytoplasm. Isoform 4: Cytoplasm. Nucleus. Isoform 5: Cytoplasm.
组织特异性
Isoform 1 is expressed predominantly in Leydig cells (at protein level). Also expressed in ovary, spleen, heart, liver, kidney and pancreas and in a number of cancer cell lines. Isoform 4 is widely expressed with highest levels in kidney, testis, uterus, ovary, prostate, placenta and fetal liver.
翻译后修饰
The N-terminus of isoform 5 is blocked.
ISGylated (Probable).
相似性
Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
Contains 1 glutaredoxin domain.

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