ATG4C | Autophagin-3 Recombinant Rabbit mAb (一抗) - WB,IHC-P,IHC-F,IF,ICC/IF | Bioss

bsm-61516R

重组兔单抗

ATG4C | Autophagin-3 Recombinant Rabbit mAb

自噬相关蛋白4C重组兔单抗

APG4-C; APG4C; AUTL1; AUTL3; HsAPG4C; Atg4cl; ATG4C_HUMAN; ATG4C; AUT-like 3 cysteine endopeptidase; Autophagy-related cysteine endopeptidase 3 (Autophagin-3); Autophagy-related protein 4 homolog C (HsAPG4C); 3.4.22.-; ATG4C_MOUSE; Autophagy-related protein 4 homolog C; autophagy related 4C cysteine peptidase; AUT (S. cerevisiae)-like 1, cysteine endopeptidase; AUT-like 1, cysteine endopeptidase (S. cerevisiae); APG4 autophagy 4 homolog C (S. cerevisiae); ATG4 autophagy related 4 homolog C (S. cerevisiae); autophagy related 4C, cysteine peptidase

Rabbit

A synthesized peptide derived from human ATG4C: 350-458/458

IgG

Liquid

affinity purified by Protein A

Recombinant

18B10

52 kDa

52 kDa

0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.

This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

Cysteine protease that plays a key role in autophagy by mediating both proteolytic activation and delipidation of ATG8 family proteins.

ATG4C

Cysteine protease ATG4C

Cytoplasm (Probable).

Highly expressed in skeletal muscle, heart, liver and testis.

Belongs to the peptidase C54 family.

Cysteine protease required for autophagy, which cleaves the C-terminal part of either MAP1LC3, GABARAPL2 or GABARAP, allowing the liberation of form I. A subpopulation of form I is subsequently converted to a smaller form (form II). Form II, with a revealed C-terminal glycine, is considered to be the phosphatidylethanolamine (PE)-conjugated form, and has the capacity for the binding to autophagosomes.