钙蛋白酶1重组兔单抗

bsm-61500R

重组兔单抗

CAPN1 Recombinant Rabbit mAb

钙蛋白酶1重组兔单抗

CANP; CANP1; CANPL1; SPG76; muCANP; muCL; CAN1_HUMAN; CAPN1; Calcium-activated neutral proteinase 1 (CANP 1); Calpain mu-type; Calpain-1 large subunit; Cell proliferation-inducing gene 30 protein; Micromolar-calpain (muCANP); 3.4.22.52;

Rabbit

A synthesized peptide derived from human Calpain 1 catalytic subunit: 154-200

IgG

Liquid

affinity purified by Protein A

Recombinant

8G1

82

75,80

10mM phosphate buffered saline(pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol.

Store at 4℃ for short term. Store at -20℃ for long term. Avoid repeated freeze/thaw cycles.

This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

钙蛋白酶(calpain)是一族钙离子依赖性的、水解半胱氨酸的蛋白酶,广泛存在于全身各脏器组织中。钙蛋白酶参与不同细胞过程,包括细胞骨架和细胞膜附着的构型重建、不同的信号转导途径和细胞凋亡等.

Calcium-regulated non-lysosomal thiol-protease which catalyzes limited proteolysis of substrates involved in cytoskeletal remodeling and signal transduction. Proteolytically cleaves CTBP1 at 'Asn-375', 'Gly-387' and 'His-409'. Cleaves and activates caspase-7 (CASP7).