Clathrin heavy chain Recombinant Rabbit mAb (一抗) - WB,IHC-P,IHC-F,IF,ICC/IF | Bioss

Rrmab?兔单抗
2026-03-02~2026-04-30,KXJ2603
Clathrin heavy chain Recombinant Rabbit mAb (一抗) - WB,IHC-P,IHC-F,IF,ICC/IF | Bioss
货号:bsm-61487R
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概述

产品编号
bsm-61487R
产品类型
重组兔单抗
英文名称
Clathrin heavy chain Recombinant Rabbit mAb
中文名称
网格蛋白重链重组兔单抗
英文别名
CHC; CHC17; CLH-17; CLTCL2; Hc; MRD56; 3110065L21Rik; CLH1_HUMAN; CLTC; Clathrin heavy chain on chromosome 17 (CLH-17); CLH17; KIAA0034; CLH1_MOUSE; CLH1_RAT;
抗体来源
Rabbit
免疫原
A synthesized peptide derived from human Clathrin heavy chain 1: 204-256
亚型
IgG
性状
Liquid
纯化方法
affinity purified by Protein A
克隆类型
Recombinant
克隆号
19G19
理论分子量
192,187 kDa
检测分子量
190 kDa
储存液
10mM phosphate buffered saline(pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol.
SWISS
Gene ID
保存条件
Store at 4℃ for short term. Store at -20℃ for long term. Avoid repeated freeze/thaw cycles.
注意事项
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
背景资料
Clathrin heavy chain proteins are composed of several functional domains, including a carboxy-terminal region that permits interaction with other heavy chain proteins within a triskelion, and a globular amino-terminal region that associates with other vesicle proteins. Adaptor proteins, such as AP2, epsin and EPS15, are responsible for the recruitment of vesicle proteins to sites of pit formation and the assembly of the clathrin-coated vesicle.
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产品应用

应用已检合格种属预测种属推荐稀释比例
WBHuman, Mouse, Rat1:500-2000
IHC-PHuman, Mouse, Rat1:50-200
IHC-FHuman, Mouse, Rat1:50-200
IFHuman, Mouse, Rat1:50-200
ICC/IFHuman, Mouse, Rat1:50-200

交叉反应

交叉反应: Human, Mouse, Rat

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靶标

基因名
CLTC
蛋白名
Clathrin heavy chain 1
亚基
Clathrin triskelions, composed of 3 heavy chains and 3 light chains, are the basic subunits of the clathrin coat. In the presence of light chains, hub assembly is influenced by both the pH and the concentration of calcium. Interacts with HIP1. Interacts with DENND1A, DENND1B and DENND1C (By similarity). May interact with OCRL. Interacts with ERBB2 (By similarity).
亚细胞定位
Cytoplasmic vesicle membrane. Membrane > coated pit. Melanosome. Cytoplasmic face of coated pits and vesicles. Identified by mass spectrometry in melanosome fractions from stage I to stage IV.
相似性
Belongs to the clathrin heavy chain family.
Contains 7 CHCR (clathrin heavy-chain) repeats.
功能
Clathrin is the major protein of the polyhedral coat of coated pits and vesicles. Two different adapter protein complexes link the clathrin lattice either to the plasma membrane or to the trans-Golgi network.

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