SAA1 Recombinant Rabbit mAb (一抗) - WB,IHC-P,IHC-F,IF | Bioss
Rrmab?兔单抗
货号：bsm-61468R
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概述
产品编号
bsm-61468R
产品类型
重组兔单抗
英文名称
SAA1 Recombinant Rabbit mAb
中文名称
血清淀粉样蛋白A重组兔单抗
英文别名
PIG4; SAA; SAA2; TP53I4; Saa-1; SAA1_HUMAN; SAA1; SAA1_MOUSE; serum amyloid A1
抗体来源
Rabbit
免疫原
A synthesized peptide derived from human Serum amyloid A: 1-122/122
亚型
IgG
性状
Liquid
纯化方法
affinity purified by Protein A
克隆类型
Recombinant
克隆号
16E9
理论分子量
14 kDa
检测分子量
13 kDa
储存液
10mM phosphate buffered saline(pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol.
研究领域
Cardiovascular > Lipids / Lipoproteins > Lipoproteins/Apolipoproteins > Apolipoproteins
Immunology > Innate Immunity > Complement > Regulatory
Immunology > Innate Immunity > Cytokines
Immunology > Innate Immunity > Macrophage / Inflamm.
Signal Transduction > Signaling Pathway > G Protein Signaling > GPCR
SWISS
Gene ID
保存条件
Store at 4℃ for short term. Store at -20℃ for long term. Avoid repeated freeze/thaw cycles.
注意事项
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
数据库链接
背景资料
Major acute phase protein.
产品应用
| 应用 | 已检合格种属 | 预测种属 | 推荐稀释比例 |
|---|---|---|---|
| WB | Human | 1:500-2000 | |
| IHC-P | Human | 1:50-200 | |
| IHC-F | Human | 1:50-200 | |
| IF | Human | 1:50-200 |
交叉反应
交叉反应: Human
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靶标
基因名
SAA1
蛋白名
Serum amyloid A-1 protein
亚基
Homohexamer; dimer of trimers. Can form amyloid fibrils after partial proteolysis; the native, undenatured protein does not form amyloid fibrils (in vitro). Apolipoprotein of the HDL complex. Binds to heparin.
亚细胞定位
Secreted.
组织特异性
Expressed by the liver; secreted in plasma (at protein level).
翻译后修饰
This protein is the precursor of amyloid protein A, which is formed by the removal of approximately 24 residues from the C-terminal end.
疾病
Reactive, secondary amyloidosis is characterized by the extracellular accumulation in various tissues of the SAA1 protein. These deposits are highly insoluble and resistant to proteolysis; they disrupt tissue structure and compromise function.
Elevated serum SAA1 protein levels may be associated with lung cancer.
Elevated serum SAA1 protein levels may be associated with lung cancer.
功能
Major acute phase reactant. Apolipoprotein of the HDL complex.
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