SDHA Recombinant Rabbit mAb (一抗) - WB,IHC-P,IHC-F,IF,Flow-Cyt,ICC/IF,IP | Bioss
Rrmab?兔单抗
货号：bsm-61435R
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常见问题
概述
产品编号
bsm-61435R
产品类型
重组兔单抗
英文名称
SDHA Recombinant Rabbit mAb
中文名称
琥珀酸脱氢酶复合体亚基A重组兔单抗
英文别名
SDHA_HUMAN; SDHA; Flavoprotein subunit of complex II (Fp); Malate dehydrogenase [quinone] flavoprotein subunit; 1.3.5.1; SDH2; SDHF; CMD1GG; FP; MC2DN1; NDAXOA; PGL5; PPGL5; SDH1; succinate dehydrogenase complex flavoprotein subunit A; succinate dehydrogenase complex, subunit A, flavoprotein (Fp); succinate dehydrogenase complex subunit A, flavoprotein (Fp); succinate dehydrogenase [ubiquinone] flavoprotein subunit; flavoprotein subunit of complex II
抗体来源
Rabbit
免疫原
A synthesized peptide derived from human SDHA: 575-621
亚型
IgG
性状
Liquid
纯化方法
affinity purified by Protein A
克隆类型
Recombinant
克隆号
6A12
理论分子量
73 kDa
检测分子量
68 kDa
储存液
10mM phosphate buffered saline(pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol.
研究领域
Cancer > Cancer Metabolism > Metabolic signaling pathway > Integration of energy metabolism
Cell Biology > Other Antibodies > Oxidative Stress
Metabolism > Pathways and Processes > Metabolic signaling pathways > Energy transfer pathways > Integration of energy
Metabolism > Pathways and Processes > Mitochondrial Metabolism > Mitochondrial markers
Metabolism > Pathways and Processes > Mitochondrial Metabolism > Oxidative phosphorylation > Complex II
Metabolism > Pathways and Processes > Redox metabolism > Oxidative stress
Metabolism > Types of disease > Cancer
Signal Transduction > Metabolism > Mitochondrial
Tags & Cell Markers > Subcellular Markers > Organelles > Mitochondria
SWISS
Gene ID
保存条件
Store at 4℃ for short term. Store at -20℃ for long term. Avoid repeated freeze/thaw cycles.
注意事项
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
背景资料
Flavoprotein (FP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone.
产品应用
| 应用 | 已检合格种属 | 预测种属 | 推荐稀释比例 |
|---|---|---|---|
| WB | Human, Mouse, Rat | 1:500-2000 | |
| IHC-P | Human, Mouse, Rat | 1:50-200 | |
| IHC-F | Human, Mouse, Rat | 1:50-200 | |
| IF | Human, Mouse, Rat | 1:50-200 | |
| Flow-Cyt | Human, Mouse, Rat | 1:50-100 | |
| ICC/IF | Human, Mouse, Rat | 1:50-200 | |
| IP | Human, Mouse, Rat | 1:20-50 |
交叉反应
交叉反应: Human, Mouse, Rat
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暂无相关产品
靶标
基因名
SDHA
蛋白名
Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial
功能
Defects in SDHA are a cause of mitochondrial complex II deficiency (MT-C2D). A disorder of the mitochondrial respiratory chain with heterogeneous clinical manifestations. Clinical features include psychomotor regression in infants, poor growth with lack of speech development, severe spastic quadriplegia, dystonia, progressive leukoencephalopathy, muscle weakness, exercise intolerance, cardiomyopathy. Some patients manifest Leigh syndrome or Kearns-Sayre syndrome.
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