XBP1 Recombinant Rabbit mAb (一抗) - IHC-P,IHC-F,IF,ICC/IF | Bioss

Name: 细胞核转录因子X盒结合蛋白重组兔单抗（XBP1 Recombinant Rabbit mAb）
Brand: 北京博奥森生物科技有限公司
SKU: bsm-61423R
Availability: InStock

Rrmab^?兔单抗

2026-07-01~2026-08-31，AB2607A 京东卡2026-07-01~2026-08-31，AB2607B 豪礼卡

一键复制说明书文献引用(1)

货号：bsm-61423R

产品详情

概述

产品编号

bsm-61423R

产品类型

重组兔单抗

英文名称

XBP1 Recombinant Rabbit mAb

中文名称

细胞核转录因子X盒结合蛋白重组兔单抗

英文别名

TREB-5; TREB5; XBP-1; XBP2; D11Ertd39e; HTF; XBP1_HUMAN; XBP1; Tax-responsive element-binding protein 5 (TREB-5); XBP1_MOUSE; XBP1_RAT; Hepatocarcinogenesis-related transcription factor (HTF); X-box binding protein 1

抗体来源

Rabbit

免疫原

A synthesized peptide derived from human XBP1: 120-160

亚型

IgG

性状

Liquid

纯化方法

affinity purified by Protein A

克隆类型

Recombinant

克隆号

10B8

理论分子量

29 kDa

检测分子量

29 kDa

储存液

10mM phosphate buffered saline(pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol.

研究领域

Epigenetics and Nuclear Signaling > Transcription > Other factors

Epigenetics and Nuclear Signaling > Transcription > Transcription Factors

SWISS

P17861

Gene ID

7494

保存条件

Store at 4℃ for short term. Store at -20℃ for long term. Avoid repeated freeze/thaw cycles.

注意事项

This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

数据库链接

Entrez Gene : 7494 Human

Entrez Gene : 22433 Mouse

Entrez Gene : 289754 Rat

Omim : 194355 Human

SwissProt : P17861 Human

SwissProt : O35426 Mouse

SwissProt : Q9R1S4 Rat

Unigene : 437638 Human

Unigene : 469937 Mouse

Unigene : 101044 Rat

产品介绍

Involvement in disease;Genetic variations in XBP1 could be associated with susceptibility to major affective disorder type 7 (MAFD7). Major affective disorders represent a class of mental disorders characterized by a disturbance in mood as their predominant feature.

背景资料

Functions as a transcription factor during endoplasmic reticulum (ER) stress by regulating the unfolded protein response (UPR). Required for cardiac myogenesis and hepatogenesis during embryonic development, and the development of secretory tissues such as exocrine pancreas and salivary gland.

基因名

XBP1

蛋白名

X-box-binding protein 1

亚细胞定位

Nucleus.

疾病

Genetic variations in XBP1 could be associated with susceptibility to major affective disorder type 7 (MAFD7) [MIM:612371]. Major affective disorders represent a class of mental disorders characterized by a disturbance in mood as their predominant feature.

相似性

Belongs to the bZIP family.
Contains 1 bZIP domain.

功能

Transcription factor essential for hepatocyte growth, the differentiation of plasma cells, the immunoglobulin secretion, and the unfolded protein response (UPR). Acts during endoplasmic reticulum stress (ER) by activating unfolded protein response (UPR) target genes via direct binding to the UPR element (UPRE). Binds DNA preferably to the CRE-like element 5'-GATGACGTG[TG]N(3)[AT]T-3', and also to some TPA response elements (TRE). Binds to the HLA DR-alpha promoter. Binds to the Tax-responsive element (TRE) of HTLV-I.