IFN gamma Recombinant Rabbit mAb (一抗) - WB,Flow-Cyt,ICC/IF | Bioss

bsm-61406R

重组兔单抗

IFN gamma Recombinant Rabbit mAb

γ-干扰素/γ-IFN重组兔单抗

IFG; IFI; IMD69; IFN-g; If2f; IFNG_HUMAN; IFNG; IFN-gamma; Immune interferon; IFNG_MOUSE; interferon gamma

Rabbit

A synthesized peptide derived from human IFN gamma: 5-50/166

IgG

Liquid

affinity purified by Protein A

Recombinant

6C10

19 kDa

25 kDa

10mM phosphate buffered saline(pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol.

Store at 4℃ for short term. Store at -20℃ for long term. Avoid repeated freeze/thaw cycles.

This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

Type II interferon produced by immune cells such as T-cells and NK cells that plays crucial roles in antimicrobial, antiviral, and antitumor responses by activating effector immune cells and enhancing antigen presentation

IFNG

Interferon gamma

Homodimer.

Secreted.

Released primarily from activated T lymphocytes.

Proteolytic processing produces C-terminal heterogeneity, with proteins ending alternatively at Gly-150, Met-157 or Gly-161.

In Caucasians, genetic variation in IFNG is associated with the risk of aplastic anemia (AA) [MIM:609135]. AA is a rare disease in which the reduction of the circulating blood cells results from damage to the stem cell pool in bone marrow. In most patients, the stem cell lesion is caused by an autoimmune attack. T-lymphocytes, activated by an endogenous or exogenous, and most often unknown antigenic stimulus, secrete cytokines, including IFN-gamma, which would in turn be able to suppress hematopoiesis.

Belongs to the type II (or gamma) interferon family.

Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons.