蛋白质二硫键异构酶重组兔单抗
Rrmab®兔单抗
货号：bsm-61394R
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概述
产品编号
bsm-61394R
产品类型
重组兔单抗
英文名称
PDIA2 Recombinant Rabbit mAb
中文名称
蛋白质二硫键异构酶重组兔单抗
英文别名
I79_007873; PDA2; PDI; PDIP; PDIR; 1810041F13Rik; Pdipl; PDIA2_HUMAN; PDIA2; Pancreas-specific protein disulfide isomerase (PDIp); 5.3.4.1; PDIA2_MOUSE;
抗体来源
Rabbit
免疫原
A synthesized peptide derived from human PDIA2: 410-450
亚型
IgG
性状
Liquid
纯化方法
affinity purified by Protein A
克隆类型
Recombinant
克隆号
9A7
理论分子量
58
检测分子量
58
储存液
10mM phosphate buffered saline(pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol.
研究领域
SWISS
Gene ID
保存条件
Store at 4℃ for short term. Store at -20℃ for long term. Avoid repeated freeze/thaw cycles.
注意事项
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
数据库链接
背景资料
Acts as an intracellular estrogen-binding protein. May be involved in modulating cellular levels and biological functions of estrogens in the pancreas. May act as a chaperone that inhibits aggregation of misfolded proteins.
产品应用
| 应用 | 已检合格种属 | 预测种属 | 推荐稀释比例 |
|---|---|---|---|
| WB | Mouse | Human, Rat | 1:500-2000 |
交叉反应
交叉反应: Mouse (predicted: Human, Rat)
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靶标
基因名
PDIA2
蛋白名
Protein disulfide-isomerase A2
亚基
Monomer; predominantly as monomer under reducing conditions. Homodimer; disulfide-linked. Part of a large chaperone multiprotein complex comprising DNAJB11, HSP90B1, HSPA5, HYOU, PDIA2, PDIA4, PDIA6, PPIB, SDF2L1, UGT1A1 and very small amounts of ERP29, but not, or at very low levels, CALR nor CANX.
亚细胞定位
Endoplasmic reticulum lumen.
组织特异性
Highly expressed in pancreas (at protein level).
翻译后修饰
The disulfide-linked homodimer exhibits an enhanced chaperone activity.
Glycosylated.
Glycosylated.
相似性
Belongs to the protein disulfide isomerase family.
Contains 2 thioredoxin domains.
Contains 2 thioredoxin domains.
功能
Acts as an intracellular estrogen-binding protein. May be involved in modulating cellular levels and biological functions of estrogens in the pancreas. May act as a chaperone that inhibits aggregation of misfolded proteins.
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