S100钙结合蛋白A6重组兔单抗
Rrmab®兔单抗
货号：bsm-61393R
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概述
产品编号
bsm-61393R
产品类型
重组兔单抗、mIHC精品抗体
英文名称
S100A6 Recombinant Rabbit mAb
中文名称
S100钙结合蛋白A6重组兔单抗
英文别名
2A9; 5B10; CABP; CACY; PRA; S10A6; CALCYCLIN; S10A6_HUMAN; S100A6; Growth factor-inducible protein 2A9; MLN 4; Prolactin receptor-associated protein (PRA); S100 calcium-binding protein A6; S10A6_MOUSE; Prolactin receptor-associated protein; S10A6_RAT;
抗体来源
Rabbit
免疫原
A synthesized peptide derived from human S100A6: 1-90/90
亚型
IgG
性状
Liquid
纯化方法
affinity purified by Protein A
克隆类型
Recombinant
克隆号
15A11
理论分子量
10
检测分子量
10
储存液
10mM phosphate buffered saline(pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol.
研究领域
SWISS
Gene ID
保存条件
Store at 4℃ for short term. Store at -20℃ for long term. Avoid repeated freeze/thaw cycles.
注意事项
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
数据库链接
背景资料
May function as calcium sensor and modulator, contributing to cellular calcium signaling. May function by interacting with other proteins, such as TPR-containing proteins, and indirectly play a role in many physiological processes such as the reorganization of the actin cytoskeleton and in cell motility. Binds 2 calcium ions. Calcium binding is cooperative.
产品应用
| 应用 | 已检合格种属 | 预测种属 | 推荐稀释比例 |
|---|---|---|---|
| WB | Human, Mouse, Rat | 1:1000-2000 | |
| IHC-P | Human, Mouse, Rat | 1:200-800 | |
| IHC-F | Human, Mouse, Rat | 1:200-800 | |
| IF | Human, Mouse, Rat | 1:200-800 | |
| Flow-Cyt | Human | Mouse, Rat | 1:50-100 |
| IP | Human, Mouse, Rat | 1:20-50 |
交叉反应
交叉反应: Human, Mouse, Rat
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靶标
基因名
S100A6
蛋白名
Protein S100-A6
亚基
Homodimer; head to tail assembly of 2 subunits. Interacts with CACYBP. Interacts with ANXA2 and ANXA11 (via N-terminus). Interacts with SUGT1. Interacts with TP53; has higher affinity for TP53 that is phosphorylated on its N-terminal domain, and lower affinity for TP53 that is phosphorylated on its C-terminal domain. Interacts with tropomyosin. Interacts with FKBP4. Interacts with CACYBP in a calcium-dependent manne.
亚细胞定位
Nucleus envelope. Cytoplasm. Cell membrane; Peripheral membrane protein; Cytoplasmic side.
翻译后修饰
The N-terminus is blocked.
相似性
Belongs to the S-100 family.Contains 2 EF-hand
功能
May function as calcium sensor and contribute to cellular calcium signaling (Potential). May function by interacting with other proteins and indirectly play a role in the reorganization of the actin cytoskeleton and in cell motility. Binds 2 calcium ions. Calcium binding is cooperative.
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