VAMP8 Recombinant Rabbit mAb (一抗) - WB,IHC-P,IHC-F,IF,Flow-Cyt,ICC/IF,IP | Bioss
Rrmab?兔单抗
货号：bsm-61388R
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概述
产品编号
bsm-61388R
产品类型
重组兔单抗
英文名称
VAMP8 Recombinant Rabbit mAb
中文名称
囊泡相关膜蛋白8重组兔单抗
英文别名
EDB; VAMP-8; endobrevin; VAMP8_HUMAN; VAMP8; Endobrevin (EDB); VAMP8_MOUSE; VAMP8_RAT; vesicle associated membrane protein 8
抗体来源
Rabbit
免疫原
A synthesized peptide derived from human VAMP8: 1-29
亚型
IgG
性状
Liquid
纯化方法
affinity purified by Protein A
克隆类型
Recombinant
克隆号
9F1
理论分子量
11 kDa
检测分子量
13 kDa
储存液
10mM phosphate buffered saline(pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol.
研究领域
SWISS
Gene ID
保存条件
Store at 4℃ for short term. Store at -20℃ for long term. Avoid repeated freeze/thaw cycles.
注意事项
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
数据库链接
背景资料
SNAREs, soluble N-ethylmaleimide-sensitive factor-attachment protein receptors, are essential proteins for fusion of cellular membranes. SNAREs localized on opposing membranes assemble to form a trans-SNARE complex, an extended, parallel four alpha-helical bundle that drives membrane fusion. VAMP8 is a SNARE involved in autophagy through the direct control of autophagosome membrane fusion with the lysososome membrane via its interaction with the STX17-SNAP29 binary t-SNARE complex.
基因名
VAMP8
蛋白名
Vesicle-associated membrane protein 8
亚基
Found in a number of SNARE complexes with NAPA, SNAP23, SNAP25, STX1A, STX4, STX7, STX8 and VTI1B (By similarity). Interacts with STX8 (By similarity).
亚细胞定位
Membrane; Single-pass type IV membrane protein.
组织特异性
Platelets.
相似性
Belongs to the synaptobrevin family.
Contains 1 v-SNARE coiled-coil homology domain.
Contains 1 v-SNARE coiled-coil homology domain.
功能
Involved in the targeting and/or fusion of transport vesicles to their target membrane. Involved for dense-granule secretion in platelets. Plays a role in regulated enzyme secretion in pancreatic acinar cells. Involved in the abscission of the midbody during cell division, which leads to completely separate daughter cells. Involved in the homotypic fusion of early and late endosomes.
产品应用
| 应用 | 已检合格种属 | 预测种属 | 推荐稀释比例 |
|---|---|---|---|
| WB | Human, Rat | Mouse | 1:500-2000 |
| IHC-P | Human, Mouse, Rat | 1:100-500 | |
| IHC-F | Human, Mouse, Rat | 1:100-500 | |
| IF | Human, Mouse, Rat | 1:100-500 | |
| Flow-Cyt | Human, Mouse, Rat | 1:100-200 | |
| ICC/IF | Human, Mouse, Rat | 1:100-200 | |
| IP | Human, Mouse, Rat | 1:50-100 |
交叉反应
交叉反应: Human, Mouse, Rat
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