溶酶体相关膜蛋白1（CD107）重组兔单抗

bsm-61375R

重组兔单抗、mIHC精品抗体

LAMP1 Recombinant Rabbit mAb

溶酶体相关膜蛋白1（CD107）重组兔单抗

CD107a; LAMPA; LGP120; LGP-120; LGP-A; Lamp-1; P2B; Perk; LAMP1_HUMAN; LAMP1; Lysosome-associated membrane protein 1; CD107 antigen-like family member A; LAMP1_MOUSE; 120 kDa lysosomal membrane glycoprotein; Lysosomal membrane glycoprotein A (LGP-A); LAMP1_RAT; 120 kDa lysosomal membrane glycoprotein (LGP-120);

Rabbit

A synthesized peptide derived from human LAMP1: 104-186/417

IgG

Liquid

affinity purified by Protein A

Recombinant

4A20

45

100-130

10mM phosphate buffered saline(pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol.

Store at 4℃ for short term. Store at -20℃ for long term. Avoid repeated freeze/thaw cycles.

This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

CD107a可很好的反映NK细胞活性，其表达水平的上调与NK分泌细胞因子的增多及NK对靶细胞的杀伤作用的增强高度相关，采用流式检测，CD107a还可鉴定出一群无细胞因子分泌的活性NK细胞。

Lysosomal membrane glycoprotein which plays an important role in lysosome biogenesis, lysosomal pH regulation, autophagy and cholesterol homeostasis. Acts as an important regulator of lysosomal lumen pH regulation by acting as a direct inhibitor of the proton channel TMEM175, facilitating lysosomal acidification for optimal hydrolase activity.