合成与降解(Synthesis and Degradation)
催化生物体内一氧化氮(NO)生成的酶。分神经型一氧化氮合成的酶(nNOS or NOS-1)、诱导型一氧化氮合成的酶(iNOS or NOS-2)、内皮型一氧化氮合成的酶(eNOS or NOS-3)。
背景资料
iNOS Produces nitric oxide (NO) which is a messenger molecule with diverse functions throughout the body. In macrophages, NO mediates tumoricidal and bactericidal actions.
产品应用
应用
已检合格种属
预测种属
推荐稀释比例
Flow-Cyt
Human
Mouse
1:50-100
交叉反应
交叉反应: Human (predicted: Mouse)
相关产品
暂无相关产品
靶标
基因名
NOS2
蛋白名
Nitric oxide synthase, inducible
亚基
Homodimer. Binds SLC9A3R1.
亚细胞定位
Cytosol
组织特异性
Expressed in the liver, retina, bone cells and airway epithelial cells of the lung. Not expressed in the platelets.
相似性
Belongs to the NOS family.
Contains 1 FAD-binding FR-type domain.
Contains 1 flavodoxin-like domain.
功能
Produces nitric oxide (NO) which is a messenger molecule with diverse functions throughout the body. In macrophages, NO mediates tumoricidal and bactericidal actions. Also has nitrosylase activity and mediates cysteine S-nitrosylation of cytoplasmic target proteins such COX2.