HSP105 Recombinant Rabbit mAb (一抗) - WB,IHC-P,IHC-F,IF,Flow-Cyt,IP | Bioss
Rrmab?兔单抗
货号：bsm-61340R
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概述
产品编号
bsm-61340R
产品类型
重组兔单抗
英文名称
HSP105 Recombinant Rabbit mAb
中文名称
热休克蛋白105重组兔单抗
英文别名
HSP105; HSP105A; HSP105B; NY-CO-25; 105kDa; Hsp110; hsp-E7I; hsp110/105; HS105_HUMAN; HSPH1; Antigen NY-CO-25; Heat shock 110 kDa protein; Heat shock protein family H member 1; KIAA0201; HS105_MOUSE; 42 degrees C-HSP; Heat shock-related 100 kDa protein E7I (HSP-E7I); HS105_RAT; heat shock protein family H (Hsp110) member 1; heat shock 105kDa/110kDa protein 1
抗体来源
Rabbit
免疫原
A synthesized peptide derived from human Hsp105: 51-99/858
亚型
IgG
性状
Liquid
纯化方法
affinity purified by Protein A
克隆类型
Recombinant
克隆号
3H12
理论分子量
97 kDa
检测分子量
110 kDa
储存液
10mM phosphate buffered saline(pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol.
SWISS
Gene ID
保存条件
Store at 4℃ for short term. Store at -20℃ for long term. Avoid repeated freeze/thaw cycles.
注意事项
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
数据库链接
背景资料
Acts as a nucleotide-exchange factor (NEF) for chaperone proteins HSPA1A and HSPA1B, promoting the release of ADP from HSPA1A/B thereby triggering client/substrate protein release.
基因名
HSPH1
蛋白名
Heat shock protein 105 kDa
亚基
Interacts with HSPA8/HSC70.
亚细胞定位
Cytoplasm.
组织特异性
Highly expressed in testis. Present at lower levels in most brain regions, except cerebellum. Overexpressed in cancer cells.
翻译后修饰
Phosphorylation on Ser-509 may be important for regulation of the HSPA8/HSC70 chaperone activity.
相似性
Belongs to the heat shock protein 70 family.
功能
Prevents the aggregation of denatured proteins in cells under severe stress, on which the ATP levels decrease markedly. Inhibits HSPA8/HSC70 ATPase and chaperone activities (By similarity).
产品应用
| 应用 | 已检合格种属 | 预测种属 | 推荐稀释比例 |
|---|---|---|---|
| WB | Human, Mouse, Rat | 1:500-2000 | |
| IHC-P | Human, Mouse, Rat | 1:100-500 | |
| IHC-F | Human, Mouse, Rat | 1:100-500 | |
| IF | Human, Mouse, Rat | 1:100-500 | |
| Flow-Cyt | Human | Mouse, Rat | 1:50-100 |
| IP | Human, Mouse, Rat | 1:20-50 |
交叉反应
交叉反应: Human, Mouse, Rat
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