TNFAIP3 Recombinant Rabbit mAb (一抗) - IHC-P,IHC-F,IF,Flow-Cyt,ICC/IF | Bioss

Name: 肿瘤坏死因子α诱导蛋白3重组兔单抗（TNFAIP3 Recombinant Rabbit mAb）
Brand: 北京博奥森生物科技有限公司
SKU: bsm-61300R
Availability: InStock

Rrmab^?兔单抗

2026-07-01~2026-08-31，AB2607A 京东卡2026-07-01~2026-08-31，AB2607B 豪礼卡

一键复制说明书

货号：bsm-61300R

产品详情

概述

产品编号

bsm-61300R

产品类型

重组兔单抗、mIHC精品抗体

英文名称

TNFAIP3 Recombinant Rabbit mAb

中文名称

肿瘤坏死因子α诱导蛋白3重组兔单抗

英文别名

TNAP3_HUMAN; TNFAIP3; TNF alpha-induced protein 3; OTU domain-containing protein 7C; Putative DNA-binding protein A20; Zinc finger protein A20; 2.3.2.-; 3.4.19.12; OTUD7C; TNAP3_MOUSE; Tnfip3; TNF alpha induced protein 3; tumor necrosis factor, alpha-induced protein 3

抗体来源

Rabbit

免疫原

A synthesized peptide derived from human TNFAIP3: 500-550/790

亚型

IgG

性状

Liquid

纯化方法

affinity purified by Protein A

克隆类型

Recombinant

克隆号

18F20

理论分子量

90 kDa

检测分子量

80 kDa

储存液

10mM phosphate buffered saline(pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol.

研究领域

Cancer > Growth factors > TNF

Epigenetics and Nuclear Signaling > Ubiquitin & Ubiquitin Like Modifiers > Deubiquitination

Immunology > Innate Immunity > Cytokines > TNF Superfamily

Microbiology > Organism > Virus > RNA Virus > ssRNA positive strand virus > SARS Coronavirus

Signal Transduction > Growth Factors/Hormones > TNF

SWISS

P21580

Gene ID

7128

保存条件

Store at 4℃ for short term. Store at -20℃ for long term. Avoid repeated freeze/thaw cycles.

注意事项

This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

数据库链接

Entrez Gene : 7128 Human

Entrez Gene : 21929 Mouse

Omim : 191163 Human

SwissProt : P21580 Human

SwissProt : Q60769 Mouse

Unigene : 211600 Human

Unigene : 116683 Mouse

产品介绍

TNFAIP3是一种泛素修饰酶，是机体重要的炎症反应负性调节因子,也是NF-κB的负调节蛋白。TNFAIP3蛋白与很多变态反应疾病的病理生理演变相关联，如：包括类风湿关节炎、冠状动脉疾病、银屑病、腹腔疾病、I型糖尿病、炎症性肠炎和系统性红斑狼疮等。

背景资料

TNFAIP3 is cytokine-inducible protein that functions to inhibit apoptosis and activation of NF-κb. Play a role in the function of the lymphoid system. Required for LPS-induced production of proinflammatory cytokines and IFN beta in LPS-tolerized macrophages.

基因名

TNFAIP3

蛋白名

Tumor necrosis factor alpha-induced protein 3

亚细胞定位

Cytoplasm. Nucleus.

相似性

Belongs to the peptidase C64 family.
Contains 7 A20-type zinc fingers.
Contains 1 OTU domain.

功能

TNFAIP3 interacts with NAF1 and inhibits TNF induced NF kappa B dependent gene expression by interfering with a RIP or TRAF2 mediated transactivation signal. It inhibits programmed cell death, has a role in the function of the lymphoid system, and may contribute to the in vivo effects of TNF.