TNAP3_HUMAN; TNFAIP3; TNF alpha-induced protein 3; OTU domain-containing protein 7C; Putative DNA-binding protein A20; Zinc finger protein A20; 2.3.2.-; 3.4.19.12; OTUD7C; TNAP3_MOUSE; Tnfip3;
抗体来源
Rabbit
免疫原
A synthesized peptide derived from human TNFAIP3: 500-550/790
亚型
IgG
性状
Liquid
纯化方法
affinity purified by Protein A
克隆类型
Recombinant
克隆号
18F20
理论分子量
90
检测分子量
82
储存液
10mM phosphate buffered saline(pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol.
TNFAIP3 is cytokine-inducible protein that functions to inhibit apoptosis and activation of NF-κb. Play a role in the function of the lymphoid system. Required for LPS-induced production of proinflammatory cytokines and IFN beta in LPS-tolerized macrophages.
产品应用
应用
已检合格种属
预测种属
推荐稀释比例
WB
Human
1:500-2000
IHC-P
Human
1:50-200
IHC-F
Human
1:50-200
IF
Human
1:50-200
Flow-Cyt
Human
1ug/Test
ICC/IF
Human
1:50-200
交叉反应
交叉反应: Human
相关产品
暂无相关产品
靶标
基因名
TNFAIP3
蛋白名
Tumor necrosis factor alpha-induced protein 3
亚细胞定位
Cytoplasm. Nucleus.
相似性
Belongs to the peptidase C64 family. Contains 7 A20-type zinc fingers. Contains 1 OTU domain.
功能
TNFAIP3 interacts with NAF1 and inhibits TNF induced NF kappa B dependent gene expression by interfering with a RIP or TRAF2 mediated transactivation signal. It inhibits programmed cell death, has a role in the function of the lymphoid system, and may contribute to the in vivo effects of TNF.