转录调节因子CEBP α重组兔单抗

Rrmab®兔单抗
2026-01-04~2026-02-28,RR26012026-01-04~2026-02-28,TR
转录调节因子CEBP α重组兔单抗
货号:bsm-61291R
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概述

产品编号
bsm-61291R
产品类型
重组兔单抗
英文名称
CEBP alpha Recombinant Rabbit mAb
中文名称
转录调节因子CEBP α重组兔单抗
英文别名
C/EBP-alpha; CEBP; C/ebpalpha; CBF-A; DBPCEP; CEBPA_HUMAN; CEBPA; C/EBP alpha; CEBPA_MOUSE; CEBPA_RAT;
抗体来源
Rabbit
免疫原
A synthesized peptide derived from human CEBP alpha: 303-358
亚型
IgG
性状
Liquid
纯化方法
affinity purified by Protein A
克隆类型
Recombinant
克隆号
5D6
理论分子量
38
检测分子量
43
储存液
10mM phosphate buffered saline(pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol.
SWISS
Gene ID
保存条件
Store at 4℃ for short term. Store at -20℃ for long term. Avoid repeated freeze/thaw cycles.
注意事项
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
背景资料
Transcription factor that coordinates proliferation arrest and the differentiation of myeloid progenitors, adipocytes, hepatocytes, and cells of the lung and the placenta. Binds directly to the consensus DNA sequence 5'-T[TG]NNGNAA[TG]-3' acting as an activator on distinct target genes.During early embryogenesis, plays essential and redundant functions with CEBPB. Essential for the transition from common myeloid progenitors (CMP) to granulocyte/monocyte progenitors (GMP). Critical for the proper development of the liver and the lung.
转录调节因子CEBP α重组兔单抗

产品应用

应用已检合格种属预测种属推荐稀释比例
WBHumanMouse, Rat1:500-2000
Flow-CytHuman, Mouse, Rat1:50-100
IPHuman, Mouse, Rat1:20-50

交叉反应

交叉反应: Human (predicted: Mouse, Rat)

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靶标

基因名
CEBPA
蛋白名
CCAAT/enhancer-binding protein alpha
亚基
Interacts with PRDM16. Binds DNA as a dimer and can form stable heterodimers with C/EBP beta and gamma. Interacts with UBN1. Interacts with HBV protein X. Interacts with ZNF638; this interaction increases transcriptional activation.
亚细胞定位
Nucleus
相似性
Belongs to the bZIP family. C/EBP subfamily.
Contains 1 bZIP domain.
功能
C/EBP is a DNA-binding protein that recognizes two different motifs: the CCAAT homology common to many promoters and the enhanced core homology common to many enhancers.

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