血管紧张素Ⅱ受体2重组兔单抗

Rrmab®兔单抗
2026-01-04~2026-02-28,RR26012026-01-04~2026-02-28,TR
血管紧张素Ⅱ受体2重组兔单抗
货号:bsm-61290R
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概述

产品编号
bsm-61290R
产品类型
重组兔单抗
英文名称
AGTR2 Recombinant Rabbit mAb
中文名称
血管紧张素Ⅱ受体2重组兔单抗
英文别名
AGTR2_HUMAN; AGTR2; Angiotensin II type-2 receptor (AT2 receptor); AGTR2_MOUSE; Q3US12_MOUSE; Angiotensin II type-2 receptor; AGTR2_RAT;
抗体来源
Rabbit
免疫原
A synthesized peptide derived from human AGTR2: 318-363
亚型
IgG
性状
Liquid
纯化方法
affinity purified by Protein A
克隆类型
Recombinant
克隆号
4F6
理论分子量
41
检测分子量
41
储存液
10mM phosphate buffered saline(pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol.
SWISS
Gene ID
保存条件
Store at 4℃ for short term. Store at -20℃ for long term. Avoid repeated freeze/thaw cycles.
注意事项
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
背景资料
Receptor for angiotensin II. Cooperates with MTUS1 to inhibit ERK2 activation and cell proliferation.
血管紧张素Ⅱ受体2重组兔单抗

产品应用

应用已检合格种属预测种属推荐稀释比例
WBHuman, Mouse, Rat1:500-2000
IPHuman, Mouse, Rat1:20-50

交叉反应

交叉反应: Human, Mouse, Rat

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靶标

基因名
AGTR2
蛋白名
Type-2 angiotensin II receptor
亚基
Interacts with MTUS1.
亚细胞定位
Cell membrane.
组织特异性
In adult, highly expressed in myometrium with lower levels in adrenal gland and fallopian tube. Very highly expressed in fetal kidney and intestine.
疾病
Defects in AGTR2 are the cause of mental retardation X-linked type 88 (MRX88) [MIM:300852]. Mental retardation is characterized by significantly below average general intellectual functioning associated with impairments in adaptative behavior and manifested during the developmental period.
相似性
Belongs to the G-protein coupled receptor 1 family.
功能
Receptor for angiotensin II. Cooperates with MTUS1 to inhibit ERK2 activation and cell proliferation.

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