前列腺素氧化环化酶1重组兔单抗

bsm-61288R

重组兔单抗、mIHC精品抗体

Cyclooxygenase 1 Recombinant Rabbit mAb

前列腺素氧化环化酶1重组兔单抗

COX1; COX3; PCOX1; PES-1; PGG/HS; PGHS-1; PGHS1; PHS1; PTGHS; Cox-1; Cox-3; PHS 1; PGH1_HUMAN; PTGS1; Cyclooxygenase-1 (COX-1); Prostaglandin H2 synthase 1 (PGH synthase 1 | PGHS-1 | PHS 1); Prostaglandin-endoperoxide synthase 1; 1.14.99.1; PGH1_MOUSE; PGH1_RAT;

Rabbit

A synthesized peptide derived from human COX 1: 100-155

IgG

Liquid

affinity purified by Protein A

Recombinant

7D4

69

70

10mM phosphate buffered saline(pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol.

Store at 4℃ for short term. Store at -20℃ for long term. Avoid repeated freeze/thaw cycles.

This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

合成与降解（Synthesis and Degradation）
COX1 前列腺素氧化环化酶-是前列腺素合成的关键酶之一，为诱导性酶，他参与细胞对生长因子、肿瘤促进因子和细胞因子的反应，这些因子均能诱导COX1表达，它也参与前列腺素的合成。

Dual cyclooxygenase and peroxidase that plays an important role in the biosynthesis pathway of prostanoids, a class of C20 oxylipins mainly derived from arachidonate ((5Z,8Z,11Z,14Z)-eicosatetraenoate, AA, C20:4(n-6)), with a particular role in the inflammatory response. The cyclooxygenase activity oxygenates AA to the hydroperoxy endoperoxide prostaglandin G2 (PGG2), and the peroxidase activity reduces PGG2 to the hydroxy endoperoxide prostaglandin H2 (PGH2), the precursor of all 2-series prostaglandins and thromboxanes.