凋亡相关斑点样蛋白ASC重组兔单抗

bsm-61273R

重组兔单抗、mIHC精品抗体

ASC/TMS1 Recombinant Rabbit mAb

凋亡相关斑点样蛋白ASC重组兔单抗

ASC; CARD5; TMS; TMS-1; TMS1; ASC_HUMAN; PYCARD; hASC; Caspase recruitment domain-containing protein 5; PYD and CARD domain-containing protein; Target of methylation-induced silencing 1;

Rabbit

KLH conjugated synthetic peptide derived from human ASC

IgG

Liquid

affinity purified by Protein A

Recombinant

6C10

22

22

10mM phosphate buffered saline(pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol.

Store at 4℃ for short term. Store at -20℃ for long term. Avoid repeated freeze/thaw cycles.

This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

Functions as a key mediator in apoptosis and inflammation.Promotes caspase-mediated apoptosis involving predominantly caspase-8 and also caspase-9 in a probable cell type-specific manner.Involved in activation of the mitochondrial apoptotic pathway, promotes caspase-8-dependent proteolytic maturation of BID independently of FADD in certain cell types and also mediates mitochondrial translocation of BAX and activates BAX-dependent apoptosis coupled to activation of caspase-9, -2 and -3.