PRPF19重组兔单抗

bsm-61268R

重组兔单抗、mIHC精品抗体

PRPF19 Recombinant Rabbit mAb

PRPF19重组兔单抗

PRP19_HUMAN; PRPF19; Nuclear matrix protein 200; PRP19/PSO4 homolog (hPso4); RING-type E3 ubiquitin transferase PRP19; Senescence evasion factor; 2.3.2.27; NMP200; PRP19; SNEV; PSO4; UBOX4; hPSO4;

Rabbit

A synthesized peptide derived from human PRPF19: 450-504/504

IgG

Liquid

affinity purified by Protein A

Recombinant

8C5

55

55

10mM phosphate buffered saline(pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol.

Store at 4℃ for short term. Store at -20℃ for long term. Avoid repeated freeze/thaw cycles.

This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

Core component of the PRP19C/Prp19 complex/NTC/Nineteen complex which is part of the spliceosome and participates in its assembly, its remodeling and is required for its activity. During assembly of the spliceosome, mediates 'Lys-63'-linked polyubiquitination of the U4 spliceosomal protein PRPF3. Ubiquitination of PRPF3 allows its recognition by the U5 component PRPF8 and stabilizes the U4/U5/U6 tri-snRNP spliceosomal complex