LSP1 Recombinant Rabbit mAb (一抗) - WB,IHC-P,IHC-F,IF,Flow-Cyt,ICC/IF | Bioss
Rrmab?兔单抗
货号：bsm-61255R
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概述
产品编号
bsm-61255R
产品类型
重组兔单抗、mIHC精品抗体
英文名称
LSP1 Recombinant Rabbit mAb
中文名称
白细胞F肌动蛋白结合蛋白重组兔单抗
英文别名
LSP1_HUMAN; LSP1; 47 kDa actin-binding protein; 52 kDa phosphoprotein (pp52); Lymphocyte-specific antigen WP34; WP34; pp52; lymphocyte specific protein 1
抗体来源
Rabbit
免疫原
A synthesized peptide derived from human LSP1: 289-339
亚型
IgG
性状
Liquid
纯化方法
affinity purified by Protein A
克隆类型
Recombinant
克隆号
5E12
理论分子量
37 kDa
检测分子量
52 kDa
储存液
10mM phosphate buffered saline(pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol.
研究领域
SWISS
Gene ID
保存条件
Store at 4℃ for short term. Store at -20℃ for long term. Avoid repeated freeze/thaw cycles.
注意事项
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
产品介绍
背景资料
LSP1 is a 52 kDa leukocyte-specific protein expressed in B cells, T cells, macrophages and neutrophils. The protein binds F-actin through its C-terminal actin-binding repeat and regulates cytoskeletal-related cellular movement such as polarization, chemotaxis and locomotion. LSP1 is a phospho-protein and has been identified as a major substrate of MAP kinase and PKC in lymphocytes and neutrophils.
基因名
LSP1
蛋白名
Lymphocyte-specific protein 1
亚基
Binds actin.
亚细胞定位
Cell membrane; Peripheral membrane protein; Cytoplasmic side.
组织特异性
Activated T-lymphocytes.
翻译后修饰
Phosphorylated by casein kinase II, protein kinase C and MAPKAPK2. Phosphorylation by PKC induces translocation from membrane to cytoplasm. Phosphorylation by MAPKAPK2 may regulate neutrophil chemotaxis (By similarity).
功能
May play a role in mediating neutrophil activation and chemotaxis (By similarity).
产品应用
| 应用 | 已检合格种属 | 预测种属 | 推荐稀释比例 |
|---|---|---|---|
| WB | Human, Mouse | Rat | 1:500-2000 |
| IHC-P | Human, Mouse, Rat | 1:50-200 | |
| IHC-F | Human, Mouse, Rat | 1:50-200 | |
| IF | Human, Mouse, Rat | 1:50-200 | |
| Flow-Cyt | Human | Mouse, Rat | 1:50-100 |
| ICC/IF | Human | Mouse, Rat | 1:50-200 |
交叉反应
交叉反应: Human, Mouse, Rat
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