SCF Recombinant Rabbit mAb (一抗) - WB,IHC-P,IHC-F,IF,Flow-Cyt,ICC/IF | Bioss

bsm-61250R

重组兔单抗

SCF Recombinant Rabbit mAb

干细胞生长因子重组兔单抗

DCUA; DFNA69; FPH2; FPHH; KL-1; Kitl; MGF; SCF; SF; SHEP7; SLF; WS2F; SCF_HUMAN; KITLG; Mast cell growth factor (MGF); Stem cell factor (SCF); c-Kit ligand; KIT ligand; mast cell growth factor; stem cell factor; steel factor; familial progressive hyperpigmentation 2

Rabbit

A synthesized peptide derived from human SCF: 40-90/273

IgG

Liquid

affinity purified by Protein A

Recombinant

7C9

31 kDa

18 kDa

10mM phosphate buffered saline(pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol.

Store at 4℃ for short term. Store at -20℃ for long term. Avoid repeated freeze/thaw cycles.

This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

Stem Cell Factor(SCF,又称Kit ligand=KITLG)—干细胞生长因子。是c-kit的配体。有膜结合型和可溶型两种存在形式。具有多向性的促生长作用。

Ligand for the receptor-type protein-tyrosine kinase KIT. Plays an essential role in the regulation of cell survival and proliferation, hematopoiesis, stem cell maintenance, gametogenesis, mast cell development, migration and function, and in melanogenesis. KITLG/SCF binding can activate several signaling pathways. Promotes phosphorylation of PIK3R1, the regulatory subunit of phosphatidylinositol 3-kinase, and subsequent activation of the kinase AKT1.

KITLG

Kit ligand

Homodimer, non-covalently linked (Probable). Heterotetramer with KIT, binding two KIT molecules; thereby mediates KIT dimerization and subsequent activation by autophosphorylation.

Isoform 1: Cell membrane; Single-pass type I membrane protein. Isoform 2: Cell membrane; Single-pass type I membrane protein. Cytoplasm, cytoskeleton. Soluble KIT ligand: Secreted.

Belongs to the SCF family.