色氨酸羟化酶重组兔单抗

bsm-61227R

重组兔单抗

TPH Recombinant Rabbit mAb

色氨酸羟化酶重组兔单抗

TPRH; TRPH; Tph; TPH1_HUMAN; TPH1; Tryptophan 5-monooxygenase 1; 1.14.16.4; TPH1_MOUSE; TPH1_RAT;

Rabbit

A synthesized peptide derived from human TPH1: 380-444

IgG

Liquid

affinity purified by Protein A

Recombinant

12A4

51

51

10mM phosphate buffered saline(pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol.

Store at 4℃ for short term. Store at -20℃ for long term. Avoid repeated freeze/thaw cycles.

This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

色氨酸在脑中首先由色氨酸羟化酶(tryoptophan hydroxylase)催化生成5羟色氨酸(5hydroxytryptophan)，再经脱羧酶作用生成5羟色胺，色氨酸羟化酶（TPH）是5-HT生物合成的限速酶，因此，色氨酸羟化酶的缺少可导致5-羟色胺的含量下降。色氨酸羟化酶主要在肝脏内代谢。

Oxidizes L-tryptophan to 5-hydroxy-l-tryptophan in the rate-determining step of serotonin biosynthesis.