细胞表面趋化因子受体3重组兔单抗

bsm-61221R

重组兔单抗

CCR3 Recombinant Rabbit mAb

细胞表面趋化因子受体3重组兔单抗

C C CKR3; CC-CKR-3; CD193; CKR 3; CKR3; CMKBR3; CC-CKR3; Cmkbr1l2; CCR3_HUMAN; CCR3; C-C CKR-3; CCR-3; Eosinophil eotaxin receptor; CCR3_MOUSE; Macrophage inflammatory protein 1-alpha receptor-like 2 (MIP-1 alpha RL2); CCR3_RAT;

Rabbit

A synthesized peptide derived from human CCR3: 300-355

IgG

Liquid

affinity purified by Protein A

Recombinant

12F9

41

55

10mM phosphate buffered saline(pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol.

Store at 4℃ for short term. Store at -20℃ for long term. Avoid repeated freeze/thaw cycles.

This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

趋化因子受体3(CCR3)主要在嗜酸粒细胞，Th2淋巴细胞，肥大细胞，支气管上皮细胞上表达， CCR3介导嗜酸粒细胞内有丝分裂原活化蛋白激酶（MAPK） 细胞外信号调节激酶-2（ERK2）、p38和JNK的活化。

Receptor for a C-C type chemokine. Binds to eotaxin, eotaxin-3, MCP-3, MCP-4, RANTES and MIP-1 delta. Subsequently transduces a signal by increasing the intracellular calcium ions level. Alternative coreceptor with CD4 for HIV-1 infection.