CCR3 Recombinant Rabbit mAb (一抗) | Bioss

bsm-61221R

重组兔单抗

CCR3 Recombinant Rabbit mAb

细胞表面趋化因子受体3重组兔单抗

C C CKR3; CC-CKR-3; CD193; CKR 3; CKR3; CMKBR3; CC-CKR3; Cmkbr1l2; CCR3_HUMAN; CCR3; C-C CKR-3; CCR-3; Eosinophil eotaxin receptor; CCR3_MOUSE; Macrophage inflammatory protein 1-alpha receptor-like 2 (MIP-1 alpha RL2); CCR3_RAT; C-C motif chemokine receptor 3; chemokine (C-C motif) receptor 3

Rabbit

A synthesized peptide derived from human CCR3: 300-355

IgG

Liquid

affinity purified by Protein A

Recombinant

12F9

41 kDa

53 kDa

0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Store at 4℃ for short term. Store at -20℃ for long term. Avoid repeated freeze/thaw cycles.

This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

趋化因子受体3(CCR3)主要在嗜酸粒细胞，Th2淋巴细胞，肥大细胞，支气管上皮细胞上表达， CCR3介导嗜酸粒细胞内有丝分裂原活化蛋白激酶（MAPK） 细胞外信号调节激酶-2（ERK2）、p38和JNK的活化。

CCR3

C-C chemokine receptor type 3

Binds to HIV-1 Tat.

Cell membrane; Multi-pass membrane protein.

In eosinophils as well as trace amounts in neutrophils and monocytes.

Belongs to the G-protein coupled receptor 1 family.

Receptor for a C-C type chemokine. Binds to eotaxin, eotaxin-3, MCP-3, MCP-4, RANTES and MIP-1 delta. Subsequently transduces a signal by increasing the intracellular calcium ions level. Alternative coreceptor with CD4 for HIV-1 infection.