mGluR5 Recombinant Rabbit mAb (一抗) - IHC-P,IHC-F,IF,Flow-Cyt,ICC/IF | Bioss

bsm-61218R

重组兔单抗

mGluR5 Recombinant Rabbit mAb

促代谢型谷氨酸受体5重组兔单抗

GPRC1E; MGLUR5; PPP1R86; mGlu5; 6430542K11Rik; Glu5R; mGluR5b; GRM5_HUMAN; GRM5; GRM5_MOUSE; GRM5_RAT; glutamate metabotropic receptor 5; glutamate receptor, metabotropic 5; protein phosphatase 1, regulatory subunit 86

Rabbit

A synthesized peptide derived from human mGluR5: 1180-1212

IgG

Liquid

affinity purified by Protein A

Recombinant

11B6

132 kDa

150 kDa

10mM phosphate buffered saline(pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol.

Store at 4℃ for short term. Store at -20℃ for long term. Avoid repeated freeze/thaw cycles.

This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

G-protein coupled receptor for glutamate. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors. Signaling activates a phosphatidylinositol-calcium second messenger system and generates a calcium-activated chloride current. Plays an important role in the regulation of synaptic plasticity and the modulation of the neural network activity.

GRM5

Metabotropic glutamate receptor 5

The PPXXF motif binds HOMER1, HOMER2 and HOMER3. Interacts with SIAH1, RYR1, RYR2, ITPR1, SHANK1, SHANK3 and GRASP. Interacts with NCDN (By similarity).

Cell Membrane

Belongs to the G-protein coupled receptor 3 family.

G-protein coupled receptor for glutamate. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteKns) and modulates the activity of down-stream effectors. Signaling activates a phosphatidylinositol-calcium second messenger system and generates a calcium-activated chloride current. Plays an important role in the regulation of synaptic plasticity and the modulation of the neural network activity.