自噬相关蛋白7重组兔单抗

Rrmab®兔单抗
2026-01-04~2026-02-28,RR26012026-01-04~2026-02-28,TR
自噬相关蛋白7重组兔单抗
货号:bsm-61206R
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概述

产品编号
bsm-61206R
产品类型
重组兔单抗
英文名称
ATG7 Recombinant Rabbit mAb
中文名称
自噬相关蛋白7重组兔单抗
英文别名
APG7-LIKE; APG7L; GSA7; SCAR31; 1810013K23Rik; Agp7; Atg7l; Gm21553; ATG7_CHICK; ATG7; ATG12-activating enzyme E1 ATG7; Autophagy-related protein 7 (APG7-like); ATG7_HUMAN; Autophagy-related protein 7 (APG7-like | hAGP7); Ubiquitin-activating enzyme E1-like protein; ATG7_MOUSE; Autophagy-related protein 7 (APG7-like | mAGP7); ATG7_RAT;
抗体来源
Rabbit
免疫原
A synthesized peptide derived from human ATG7: 680-703
亚型
IgG
性状
Liquid
纯化方法
affinity purified by Protein A
克隆类型
Recombinant
克隆号
16D1
理论分子量
78
检测分子量
78
储存液
10mM phosphate buffered saline(pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol.
SWISS
Gene ID
保存条件
Store at 4℃ for short term. Store at -20℃ for long term. Avoid repeated freeze/thaw cycles.
注意事项
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
背景资料
E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy.
自噬相关蛋白7重组兔单抗自噬相关蛋白7重组兔单抗自噬相关蛋白7重组兔单抗

产品应用

应用已检合格种属预测种属推荐稀释比例
WBHuman1:1000-2000
IHC-PHuman1:50-200
IHC-FHuman1:50-200
IFHuman1:50-200
Flow-CytHuman1:50-100
ICC/IFHuman1:50-200
IPHuman1:20-50

交叉反应

交叉反应: Human

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靶标

基因名
ATG7
蛋白名
Ubiquitin-like modifier-activating enzyme ATG7
亚基
Homodimer. Interacts with ATG3 and ATG12. The complex, composed of ATG3 and ATG7, plays a role in the conjugation of ATG12 to ATG5.
亚细胞定位
Cytoplasm (Probable).
组织特异性
Widely expressed, especially in kidney, liver, lymph nodes and bone marrow.
相似性
Belongs to the ATG7 family.
功能
Functions as an E1 enzyme essential for multisubstrates such as ATG8-like proteins and ATG12. Forms intermediate conjugates with ATG8-like proteins (GABARAP, GABARAPL1, GABARAPL2 or MAP1LC3A). PE-conjugation to ATG8-like proteins is essential for autophagy. Also acts as an E1 enzyme for ATG12 conjugation to ATG5 and ATG3.

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