Chromatin reader protein that recognizes and binds acetylated histones and plays a key role in transmission of epigenetic memory across cell divisions and transcription regulation.
产品应用
应用
已检合格种属
预测种属
推荐稀释比例
IHC-P
Human, Mouse
1:50-200
IHC-F
Human, Mouse
1:50-200
IF
Human, Mouse
1:50-200
交叉反应
交叉反应: Human, Mouse
相关产品
暂无相关产品
靶标
基因名
BRD4
蛋白名
Bromodomain-containing protein 4
亚基
Associated with chromosomes during mitosis. Interacts with bovine papillomavirus type 1 regulatory protein E2.
亚细胞定位
Nucleus.
组织特异性
Ubiquitously expressed.
疾病
Note=A chromosomal aberration involving BRD4 is found in a rare, aggressive, and lethal carcinoma arising in midline organs of young people. Translocation t(15;19)(q14;p13) with NUT which produces a BRD4-NUT fusion protein.
相似性
Contains 2 bromo domains.
功能
Plays a role in a process governing chromosomal dynamics during mitosis (By similarity).